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Metaproterenol Side Effects

Medically reviewed by Last updated on Jul 4, 2022.


More frequently reported side effects include: tremor. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to metaproterenol: oral syrup, oral tablet

Side effects requiring immediate medical attention

Along with its needed effects, metaproterenol may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking metaproterenol:

More common

Less common

  • Shakiness in the legs, arms, hands, or feet
  • trembling or shaking of the hands or feet
  • worsening of asthma


Get emergency help immediately if any of the following symptoms of overdose occur while taking metaproterenol:

Symptoms of overdose

  • Arm, back, or jaw pain
  • chest discomfort
  • chest tightness or heaviness
  • confusion
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • dry mouth
  • general feeling of discomfort or illness
  • shortness of breath
  • sleeplessness
  • unable to sleep

Side effects not requiring immediate medical attention

Some side effects of metaproterenol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Abdominal or stomach pain


  • Bad, unusual, or unpleasant (after) taste
  • change in appetite
  • drowsiness
  • dry mouth or throat
  • itching skin
  • pain
  • raised red swellings on the skin, lips, tongue, or in the throat
  • tightening of the muscles
  • weakness

For Healthcare Professionals

Applies to metaproterenol: compounding powder, inhalation aerosol, inhalation aerosol with adapter, inhalation solution, oral syrup, oral tablet


Very common (10% or more): Tachycardia (17.1%)

Common (1% to 10%): Palpitations

Rare (less than 0.1%): Hypertension, chest pain[Ref]


Very common (10% or more): Tremor (16.9%)

Uncommon (0.1% to 1%): Spasms, chills[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness,

Uncommon (0.1% to 1%): Syncope, clonus noted on flexing foot[Ref]


Very common (10% or more): Nervousness (20.2%)

Common (1% to 10%): Insomnia

Uncommon (0.1% to 1%): Chatty[Ref]


Common (1% to 10%): Asthma exacerbation

Uncommon (0.1% to 1%): Coughing[Ref]


Common (1% to 10%): Nausea, gastrointestinal distress, diarrhea

Uncommon (0.1% to 1%): Vomiting, dry mouth/throat, laryngeal changes[Ref]


Common (1% to 10%): Fatigue

Uncommon (0.1% to 1%): Edema, sensory disturbances, weakness, pain, bad taste, feverish, flu symptoms, facial and finger puffiness[Ref]


Uncommon (0.1% to 1%): Pruritus, diaphoresis, hives[Ref]


Uncommon (0.1% to 1%): Blurred vision[Ref]


Uncommon (0.1% to 1%): Appetite changes[Ref]


1. "Product Information. Metaproterenol Sulfate (metaproterenol)." Par Pharmaceutical Inc (2022):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.