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Lasix Side Effects

Generic name: furosemide

Medically reviewed by Drugs.com. Last updated on Apr 27, 2023.

Note: This document contains side effect information about furosemide. Some dosage forms listed on this page may not apply to the brand name Lasix.

For Healthcare Professionals

Applies to furosemide: compounding powder, injectable solution, intravenous solution, oral liquid, oral solution, oral tablet, subcutaneous kit.

Metabolic

Common (1% to 10%): Hyponatremia, hypochloremia, hypokalemia, blood cholesterol increased, blood uric acid increased, gout

Uncommon (0.1% to 1%): Thirst, glucose tolerance decreased

Rare (0.01% to 0.1%): Anorexia, serum triglycerides increased

Frequency not reported: Hyperglycemia, diabetes mellitus, hyperuricemia, metabolic alkalosis, hypocalcemia, hypomagnesemia, hypovolemia, dehydration, tetany, serum potassium decreased, Pseudo-Bartter syndrome, electrolyte disturbances, serum calcium decreased[Ref]

Hematologic

Common (1% to 10%): Hemoconcentration

Uncommon (0.1% to 1%): Thrombocytopenia

Rare (0.01% to 0.1%): Eosinophilia, leukopenia, bone marrow depression

Very rare (less than 0.01%): Hemolytic anemia, aplastic anemia, agranulocytosis

Frequency not reported: Anemia, thrombophilia[Ref]

Genitourinary

Common (1% to 10%): Urine volume increased

Frequency not reported: Glycosuria, bladder spasm, urinary retention, urinary incontinence[Ref]

Dermatologic

Uncommon (0.1% to 1%): Pruritus, bullous exanthema, rash, urticaria, purpura, erythema multiforme, exfoliative dermatitis, photosensitivity

Rare (less than 0.1%): Lyell's syndrome and Stevens-Johnson syndrome, acute generalized exanthematous pustulosis, drug rash with eosinophilia and systemic symptoms

Frequency not reported: Toxic epidermal necrolysis, bullous pemphigoid, sweating[Ref]

Gastrointestinal

Uncommon (0.1% to 1%): Dry mouth, nausea, bowel motility disturbances, vomiting, diarrhea, constipation

Rare (less than 0.1%): Gastric distress, acute pancreatitis

Frequency not reported: Pancreatitis, oral and gastric irritation, cramping[Ref]

Renal

Uncommon (0.1% to 1%): Blood creatinine increased, urea increased

Rare (less than 0.1%): Interstitial nephritis, acute renal failure

Frequency not reported: Nephrocalcinosis in premature infants, nephrolithiasis in premature infants, GFR decreased, tubulointerstitial nephritis[Ref]

Other

Uncommon (0.1% to 1%): Deafness, fatigue

Rare (less than 0.1%): Sensation of pressure in the head, dysacusis, asthenia, fever, febrile conditions, malaise

Frequency not reported: Weakness, sudden death, hearing disorders, hearing loss, paradoxical swelling[Ref]

Cardiovascular

Uncommon (0.1% to 1%): Cardiac arrhythmia

Rare (less than 0.1%): Vasculitis

Frequency not reported: Systemic vasculitis, necrotizing angiitis, orthostatic hypotension, thrombophlebitis, acute hypotension, circulatory collapse, persistent patent ductus arteriosus during the first few weeks of life in premature infants with respiratory distress syndrome, blood pressure decreased, shock, hypotension, thrombosis, orthostatic blood pressure decreased[Ref]

Ocular

Uncommon (0.1% to 1%): Visual disturbance

Rare (less than 0.1%): Myopia aggravated, blurred vision

Frequency not reported: Blurred vision, xanthopsia[Ref]

Nervous system

Rare (0.01% to 0.1%): Paresthesia, vertigo, dizziness, sleepiness, tinnitus, hyperosmolar coma

Frequency not reported: Hepatic encephalopathy, headache, fainting and loss of consciousness, drowsiness, lethargy, sweet taste[Ref]

Musculoskeletal

Rare (less than 0.1%): Lupus erythematosus activation or exacerbation, leg muscle cramps, chronic arthritis

Frequency not reported: Muscle spasm, rhabdomyolysis[Ref]

Immunologic

Rare (less than 0.1%): Severe anaphylactic or anaphylactoid reactions

Frequency not reported: Allergic reactions[Ref]

Hepatic

Very rare (less than 0.01%): Jaundice, hepatic ischemia, liver enzymes increased

Frequency not reported: Abnormal hepatic function, cholestasis, bile flow increased, biliary tree distended[Ref]

Psychiatric

Frequency not reported: Restlessness, psychiatric disorder, apathy[Ref]

Frequently asked questions

References

1. Product Information. Lasix (furosemide). sanofi-aventis. 2007;PROD.

2. Cerner Multum, Inc. UK Summary of Product Characteristics.

3. Cerner Multum, Inc. Australian Product Information.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.