Ceftibuten Side Effects

Medically reviewed by Drugs.com. Last updated on Sep 7, 2020.

• Consumer
• Professional

In Summary

More frequently reported side effects include: nausea. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to ceftibuten: oral capsules, oral for suspension

Side effects include:

GI effects (e.g., nausea, diarrhea, dyspepsia, vomiting, abdominal pain), headache, dizziness, increased BUN concentrations, eosinophilia.

For Healthcare Professionals

Applies to ceftibuten: oral capsule, oral powder for reconstitution

General

This drug was generally well tolerated. In clinical trials, 2% of patients discontinued medication due to adverse events, primarily diarrhea, nausea, or vomiting, and 0.3% discontinued due to rash or pruritus.^[Ref]

Gastrointestinal

The onset of pseudomembranous colitis symptoms has been reported during or after antibacterial therapy.^[Ref]

Common (1% to 10%): Nausea, diarrhea, dyspepsia, abdominal pain, vomiting

Uncommon (0.1% to 1%): Constipation, dry mouth, eructation, flatulence, loose stools

Postmarketing reports: Melena

Cephalosporin-class:

-Frequency not reported: Pseudomembranous colitis^[Ref]

Nervous system

Some cephalosporins have been associated with seizures, especially in patients with renal dysfunction whose dose was not reduced.^[Ref]

Common (1% to 10%): Headache, dizziness

Uncommon (0.1% to 1%): Somnolence, taste perversion, paresthesia

Frequency not reported: Hyperkinesia

Postmarketing reports: Aphasia

Cephalosporin-class:

-Frequency not reported: Seizures^[Ref]

Hepatic

Common (1% to 10%): Increased ALT, increased bilirubin

Uncommon (0.1% to 1%): Increased AST

Postmarketing reports: Jaundice

Cephalosporin-class:

-Frequency not reported: Hepatic cholestasis^[Ref]

Hematologic

Common (1% to 10%): Increased eosinophils, decreased hemoglobin

Uncommon (0.1% to 1%): Increased platelets, decreased platelets, decreased leukocytes

Cephalosporin-class:

-Frequency not reported: Aplastic anemia, hemolytic anemia, prolonged prothrombin time, hemorrhage, neutropenia, pancytopenia, agranulocytosis^[Ref]

Renal

Common (1% to 10%): Increased BUN

Uncommon (0.1% to 1%): Increased creatinine

Cephalosporin-class:

-Frequency not reported: Renal dysfunction, toxic nephropathy^[Ref]

Dermatologic

Uncommon (0.1% to 1%): Pruritus, rash, urticaria

Frequency not reported: Diaper dermatitis

Postmarketing reports: Stevens-Johnson syndrome, toxic epidermal necrolysis

Cephalosporin-class:

-Frequency not reported: Stevens-Johnson syndrome, erythema multiforme^[Ref]

Other

Uncommon (0.1% to 1%): Fatigue, moniliasis, increased alkaline phosphatase

Frequency not reported: Fever, rigors, transient increases in lactate dehydrogenase

Cephalosporin-class:

-Frequency not reported: Drug fever^[Ref]

Metabolic

Uncommon (0.1% to 1%): Anorexia

Frequency not reported: Dehydration

Cephalosporin-class:

-Frequency not reported: False-positive test for urinary glucose^[Ref]

Respiratory

Uncommon (0.1% to 1%): Dyspnea, nasal congestion

Postmarketing reports: Stridor^[Ref]

Genitourinary

Uncommon (0.1% to 1%): Dysuria, vaginitis

Frequency not reported: Hematuria^[Ref]

Psychiatric

Frequency not reported: Agitation, irritability, insomnia

Postmarketing reports: Psychosis^[Ref]

Hypersensitivity

Postmarketing reports: Serum sickness-like reactions

Cephalosporin-class:

-Frequency not reported: Allergic reactions, anaphylaxis^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer