Cedax Side Effects

Generic name: ceftibuten

Medically reviewed by Drugs.com. Last updated on Sep 6, 2024.

Note: This document provides detailed information about Cedax Side Effects associated with ceftibuten. Some dosage forms listed on this page may not apply specifically to the brand name Cedax.

Applies to ceftibuten: oral capsule, oral powder for reconstitution.

Get emergency medical help if you have any of these signs of an allergic reaction while taking ceftibuten (the active ingredient contained in Cedax) hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• diarrhea that is watery or bloody;

• fever, chills, body aches, flu symptoms;

• unusual bleeding;

• blood in your urine;

• seizure (convulsions);

• pale or yellowed skin, dark colored urine, fever, confusion or weakness;

• jaundice (yellowing of the skin or eyes);

• fever, swollen glands, rash or itching, joint pain, or general ill feeling;

• fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or

• increased thirst, loss of appetite, swelling, weight gain, feeling short of breath, urinating less than usual or not at all.

Less serious side effects of ceftibuten may include:

• nausea, vomiting, stomach pain, upset stomach, belching, constipation, mild diarrhea;

• stiff or tight muscles;

• numbness or tingly feeling;

• headache, dizziness, drowsiness, tired feeling;

• feeling agitated, irritable, restless, or hyperactive;

• dry mouth;

• white patches or sores inside your mouth or on your lips;

• unusual or unpleasant taste in your mouth;

• stuffy nose, noisy breathing;

• sleep problems (insomnia);

• mild itching or skin rash;

• vaginal itching or discharge;

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

For healthcare professionals

Applies to ceftibuten: oral capsule, oral powder for reconstitution.

General adverse events

This drug was generally well tolerated. In clinical trials, 2% of patients discontinued medication due to adverse events, primarily diarrhea, nausea, or vomiting, and 0.3% discontinued due to rash or pruritus.^[Ref]

Gastrointestinal

• Common (1% to 10%): Nausea, diarrhea, dyspepsia, abdominal pain, vomiting
• Uncommon (0.1% to 1%): Constipation, dry mouth, eructation, flatulence, loose stools
• Postmarketing reports: Melena

Cephalosporin-class:

• Frequency not reported: Pseudomembranous colitis^[Ref]

The onset of pseudomembranous colitis symptoms has been reported during or after antibacterial therapy.^[Ref]

Nervous system

• Common (1% to 10%): Headache, dizziness
• Uncommon (0.1% to 1%): Somnolence, taste perversion, paresthesia
• Frequency not reported: Hyperkinesia
• Postmarketing reports: Aphasia

Cephalosporin-class:

• Frequency not reported: Seizures^[Ref]

Some cephalosporins have been associated with seizures, especially in patients with renal dysfunction whose dose was not reduced.^[Ref]

Hepatic

• Common (1% to 10%): Increased ALT, increased bilirubin
• Uncommon (0.1% to 1%): Increased AST
• Postmarketing reports: Jaundice

Cephalosporin-class:

• Frequency not reported: Hepatic cholestasis^[Ref]

Hematologic

• Common (1% to 10%): Increased eosinophils, decreased hemoglobin
• Uncommon (0.1% to 1%): Increased platelets, decreased platelets, decreased leukocytes

Cephalosporin-class:

• Frequency not reported: Aplastic anemia, hemolytic anemia, prolonged prothrombin time, hemorrhage, neutropenia, pancytopenia, agranulocytosis^[Ref]

Renal

• Common (1% to 10%): Increased BUN
• Uncommon (0.1% to 1%): Increased creatinine

Cephalosporin-class:

• Frequency not reported: Renal dysfunction, toxic nephropathy^[Ref]

Dermatologic

• Uncommon (0.1% to 1%): Pruritus, rash, urticaria
• Frequency not reported: Diaper dermatitis
• Postmarketing reports: Stevens-Johnson syndrome, toxic epidermal necrolysis

Cephalosporin-class:

• Frequency not reported: Stevens-Johnson syndrome, erythema multiforme^[Ref]

Other

• Uncommon (0.1% to 1%): Fatigue, moniliasis, increased alkaline phosphatase
• Frequency not reported: Fever, rigors, transient increases in lactate dehydrogenase

Cephalosporin-class:

• Frequency not reported: Drug fever^[Ref]

Metabolic

• Uncommon (0.1% to 1%): Anorexia
• Frequency not reported: Dehydration

Cephalosporin-class:

• Frequency not reported: False-positive test for urinary glucose^[Ref]

Respiratory

• Uncommon (0.1% to 1%): Dyspnea, nasal congestion
• Postmarketing reports: Stridor^[Ref]

Genitourinary

• Uncommon (0.1% to 1%): Dysuria, vaginitis
• Frequency not reported: Hematuria^[Ref]

Psychiatric

• Frequency not reported: Agitation, irritability, insomnia
• Postmarketing reports: Psychosis^[Ref]

Hypersensitivity

• Postmarketing reports: Serum sickness-like reactions

Cephalosporin-class:

• Frequency not reported: Allergic reactions, anaphylaxis^[Ref]

See also:

Further information

Cedax side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer