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Capozide 25/25 Side Effects

Generic name: captopril / hydrochlorothiazide

Medically reviewed by Drugs.com. Last updated on Mar 2, 2024.

Note: This document provides detailed information about Capozide 25/25 Side Effects associated with captopril / hydrochlorothiazide. Some dosage forms listed on this page may not apply specifically to the brand name Capozide 25/25.

Applies to captopril / hydrochlorothiazide: oral tablet.

Important warnings This medicine can cause some serious health issues

Oral route (tablet)

Use in Pregnancy. When used in pregnancy during the second and third trimesters, ACE inhibitors can cause injury and even death to the developing fetus.

When pregnancy is detected, captopril and hydrochlorothiazide should be discontinued as soon as possible.

Serious side effects of Capozide 25/25

Along with its needed effects, captopril / hydrochlorothiazide may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking captopril / hydrochlorothiazide:

More common

  • black, tarry stools
  • chest pain
  • chills
  • cough
  • fever
  • painful or difficult urination
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • swollen glands
  • trouble breathing
  • unusual bleeding or bruising
  • unusual tiredness or weakness

Less common

  • blurred vision
  • cloudy urine
  • confusion
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fast, pounding, or irregular heartbeat or pulse
  • sweating

Rare

  • arm, back, or jaw pain or discomfort
  • bloody urine
  • chest discomfort, tightness, or heaviness
  • decreased blood pressure
  • decreased frequency or amount of urine
  • dilated neck veins
  • increased need to urinate
  • increased thirst
  • irregular breathing
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • loss of appetite
  • lower back or side pain
  • nausea
  • paleness or cold feeling in fingertips and toes
  • passing urine more often
  • problems in urination or increase in amount of urine
  • swelling of the face, fingers, feet, or lower legs
  • tingling or pain in the fingers or toes when exposed to cold
  • vomiting
  • weight gain

incidence not known

Other side effects of Capozide 25/25

Some side effects of captopril / hydrochlorothiazide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • difficulty in moving
  • itching skin, rash
  • muscle pain or stiffness
  • pain in joints

Less common

  • change or loss of taste

For healthcare professionals

Applies to captopril / hydrochlorothiazide: oral tablet.

Gastrointestinal

Captopril:

Hydrochlorothiazide:

Nervous system

Captopril:

Hydrochlorothiazide:

Dermatologic

Captopril:

Hydrochlorothiazide:

Other

Captopril:

Hydrochlorothiazide:

Cardiovascular

Captopril:

Hydrochlorothiazide:

Respiratory

Captopril:

Hydrochlorothiazide:

Psychiatric

Captopril:

Hydrochlorothiazide:

Genitourinary

Captopril:

Hydrochlorothiazide:

Metabolic

Captopril:

Hydrochlorothiazide:

Renal

Captopril:

Hydrochlorothiazide:

Hematologic

Captopril:

Hydrochlorothiazide:

Immunologic

Captopril:

Hydrochlorothiazide:

Hepatic

Captopril:

Hydrochlorothiazide:

Musculoskeletal

Captopril:

Hydrochlorothiazide:

Ocular

Captopril:

Hydrochlorothiazide:

References

1. "Product Information. Capozide 25/15 (captopril-hydrochlorothiazide)." Bristol-Myers Squibb

2. Cerner Multum, Inc. "UK Summary of Product Characteristics."

Further information

Capozide 25/25 side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.