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Astepro Side Effects

Generic name: azelastine nasal

Medically reviewed by Last updated on Sep 10, 2023.

Note: This document contains side effect information about azelastine nasal. Some dosage forms listed on this page may not apply to the brand name Astepro.

Applies to azelastine nasal: nasal spray.

Serious side effects of Astepro

Along with its needed effects, azelastine nasal (the active ingredient contained in Astepro) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking azelastine nasal:

More common

Less common


Other side effects of Astepro

Some side effects of azelastine nasal may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Less common

For Healthcare Professionals

Applies to azelastine nasal: nasal spray.


The most commonly reported adverse reactions were headache, bitter taste, sinusitis, and epistaxis.[Ref]


Common (1% to 10%): Epistaxis, nasal discomfort, upper respiratory infection, sneezing, nasal mucosal ulceration, sinusitis

Postmarketing reports: Nasal burning, throat irritation, dyspnea, paroxysmal sneezing[Ref]


Postmarketing reports: Anaphylactoid reaction[Ref]


Postmarketing reports: Application site irritation[Ref]

Nervous system

Very common (10% or more): Bitter taste (10%)

Common (1% to 10%): Headache, somnolence, dysgeusia

Postmarketing reports: Sweet taste, confusion, dizziness, nervousness, paraesthesia, parosmia, involuntary muscle contractions, disturbance or loss of sense of smell and/or taste[Ref]


Postmarketing reports: Atrial fibrillation, chest pain, hypertension, palpitations, tachycardia[Ref]


Very rare (less than 0.01%): Urticaria, pruritus, rash[Ref]


Postmarketing reports: Abdominal pain, nausea[Ref]


Common (1% to 10%): Fatigue

Postmarketing reports: Facial edema, tolerance[Ref]


Postmarketing reports: Blurred vision, xerophthalmia[Ref]


Postmarketing reports: Urinary retention[Ref]


1. Product Information. Astelin (azelastine nasal). Carter Wallace.

2. Cerner Multum, Inc. UK Summary of Product Characteristics.

3. Product Information. Astepro (azelastine nasal). Meda Pharmaceuticals. 2009.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.