Skip to main content

Altace Side Effects

Generic name: ramipril

Medically reviewed by Last updated on Oct 26, 2023.

Note: This document contains side effect information about ramipril. Some dosage forms listed on this page may not apply to the brand name Altace.

Applies to ramipril: oral capsule.


Oral route (Capsule; Tablet)

When pregnancy is detected, discontinue ramipril as soon as possible. Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus.

Serious side effects of Altace

Along with its needed effects, ramipril (the active ingredient contained in Altace) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking ramipril:

More common

Less common


Other side effects of Altace

Some side effects of ramipril may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Less common


For Healthcare Professionals

Applies to ramipril: oral capsule, oral tablet.


The most common adverse reaction is hypotension.[Ref]


Very common (10% or more): Hypotension (11%)

Common (1% to 10%): Angina pectoris, postural hypotension, orthostatic blood pressure decreased

Uncommon (0.1% to 1%): Symptomatic hypotension, myocardial ischemia, myocardial infarction, tachycardia, arrhythmia, palpitation, flushing

Rare (less than 0.1%): Vascular stenosis, hypoperfusion, vasculitis

Frequency not reported: Disturbed orthostatic regulation, Raynaud's phenomenon[Ref]


Common (1% to 10%): Nausea, vomiting, diarrhea, gastrointestinal inflammation, digestive disturbances, abdominal discomfort, dyspepsia

Uncommon (0.1% to 1%): Pancreatitis, pancreatic enzymes increased, abdominal pain, small bowel angioedema, gastritis, constipation, dry mouth

Rare (less than 0.1%): Glossitis

Frequency not reported: Dysphagia, gastroenteritis, increased salivation, gastric pain, aphthous stomatitis[Ref]


Common (1% to 10%): Fatigue, asthenia, vertigo, bronchitis, sinusitis, chest pain

Uncommon (0.1% to 1%): Peripheral edema, pyrexia, libido decreased

Rare (less than 0.1%): Conjunctivitis, hearing impaired, tinnitus

Frequency not reported: Hearing loss, edema, malaise, gynecomastia[Ref]


Common (1% to 10%): Cough, nonproductive tickling cough, cough increased, dyspnea

Uncommon (0.1% to 1%): Bronchospasm, asthma aggravated

Frequency not reported: Eosinophilic pneumonitis, epistaxis, nasal congestion[Ref]


Uncommon (0.1% to 1%): Depressed mood, anxiety, nervousness, restlessness, sleep disorder

Rare (less than 0.1%): Confusional state

Frequency not reported: Depression, insomnia, disturbance in attention[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness, syncope

Uncommon (0.1% to 1%): Paresthesia, dysgeusia, ageusia, somnolence

Rare (less than 0.1%): Tremor, balance disorder

Frequency not reported: Smell disturbance, amnesia, convulsions, neuralgia, neuropathy, cerebral ischemia, ischemic stroke, transient ischemic attack, psychomotor skills impaired, burning sensation, parosmia[Ref]


Common (1% to 10%): Muscle spasm, myalgia

Uncommon (0.1% to 1%): Arthralgia

Frequency not reported: Arthritis[Ref]


Common (1% to 10%): Maculopapular rash

Uncommon (0.1% to 1%): Pruritus, hyperhidrosis

Rare (less than 0.1%): Exfoliative dermatitis, urticaria, onycholysis

Frequency not reported: Purpura, pemphigus, pemphigoid, erythema multiforme, toxic epidermal necrolysis, Stevens Johnson syndrome, sweating increased, alopecia, psoriasis aggravated, dermatitis psoriasiform, lichenoid exanthema, enanthema[Ref]


Common (1% to 10%): Abnormal kidney function

Uncommon (0.1% to 1%): Renal impairment, acute renal failure[Ref]


Common (1% to 10%): Creatinine increased, blood potassium increased

Uncommon (0.1% to 1%): Anorexia, decreased appetite, BUN increased

Frequency not reported: Weight gain, hyponatremia, loss of appetite, uric acid elevated, blood glucose elevated, blood sodium decreased

Postmarketing reports: Hypoglycemia[Ref]


Uncommon (0.1% to 1%): Worsening of preexisting proteinuria, urine output increased, transient erectile impotence

Frequency not reported: Proteinuria, impotence[Ref]


Uncommon (0.1% to 1%): Visual disturbance, blurred vision[Ref]


Uncommon (0.1% to 1%): Eosinophilia, hemoglobin or hematocrit decreased

Rare (less than 0.1%): Neutropenia, agranulocytosis, white blood cell count decreased, red blood cell count decreased, platelet count decreased

Frequency not reported: Pancytopenia, hemolytic anemia, thrombocytopenia, leucopenia, bone marrow failure[Ref]


Uncommon (0.1% to 1%): Hepatic enzymes increased, conjugated bilirubin increased

Rare (less than 0.1%): Cholestatic jaundice, hepatocellular damage

Frequency not reported: Hepatic failure, hepatitis, jaundice, acute liver failure, hepatocellular damage, cholestatic hepatitis, cytolytic hepatitis, serum bilirubin elevated[Ref]


Uncommon (0.1% to 1%): Angioneurotic edema, angioedema

Very rare (less than 0.01%): Photosensitivity

Frequency not reported: Anaphylactic reaction, anaphylactoid reaction, apparent hypersensitivity reaction, antinuclear antibody increased[Ref]


Frequency not reported: Syndrome of inappropriate antidiuretic hormone secretion[Ref]

Frequently asked questions


1. Cerner Multum, Inc. "UK Summary of Product Characteristics."

2. Cerner Multum, Inc. "Australian Product Information."

3. (2001) "Product Information. Altace (ramipril)." Hoechst Marion Roussel

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.