What is Metoprolol Succinate ER?
Metoprolol Succinate ER is a beta-blocker that affects the heart and circulation (blood flow through arteries and veins).
Metoprolol Succinate ER may also be used for other purposes not listed in this medication guide.
You should not use Metoprolol Succinate ER if you have a serious heart problem (heart block, sick sinus syndrome, slow heart rate), severe circulation problems, severe heart failure, or a history of slow heart beats that caused fainting.
Before taking this medicine
You should not use this medicine if you are allergic to Metoprolol Succinate ER, or other beta-blockers (atenolol, carvedilol, labetalol, nadolol, nebivolol, propranolol, sotalol, and others), or if you have:
a serious heart problem such as heart block, sick sinus syndrome, or slow heart rate;
severe circulation problems;
severe heart failure (that required you to be in the hospital); or
a history of slow heart beats that have caused you to faint.
Tell your doctor if you have ever had:
diabetes (taking Metoprolol Succinate ER may make it harder for you to tell when you have low blood sugar);
congestive heart failure;
problems with circulation (such as Raynaud's syndrome);
a thyroid disorder; or
pheochromocytoma (tumor of the adrenal gland).
Do not give this medicine to a child without medical advice.
Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether Metoprolol Succinate ER will harm an unborn baby. However, having high blood pressure during pregnancy may cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of treating hypertension may outweigh any risks to the baby.
How should I take Metoprolol Succinate ER?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Metoprolol Succinate ER should be taken with a meal or just after a meal.
Take the medicine at the same time each day.
Swallow the capsule whole and do not crush, chew, break, or open it.
A Toprol XL tablet can be divided in half if your doctor has told you to do so. Swallow the half-tablet whole, without chewing or crushing.
Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
You will need frequent medical tests, and your blood pressure will need to be checked often.
If you need surgery, tell the surgeon ahead of time that you are using Metoprolol Succinate ER.
You should not stop using Metoprolol Succinate ER suddenly. Stopping suddenly may make your condition worse.
If you have high blood pressure, keep using Metoprolol Succinate ER even if you feel well. High blood pressure often has no symptoms. You may need to use Metoprolol Succinate ER for the rest of your life.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking Metoprolol Succinate ER?
Avoid driving or hazardous activity until you know how Metoprolol Succinate ER will affect you. Your reactions could be impaired.
Drinking alcohol can increase certain side effects of Metoprolol Succinate ER.
Metoprolol Succinate ER side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
very slow heartbeats;
a light-headed feeling, like you might pass out;
shortness of breath (even with mild exertion), swelling, rapid weight gain; or
cold feeling in your hands and feet.
Common side effects may include:
dizziness, tired feeling;
depression, confusion, memory problems;
nightmares, trouble sleeping;
mild itching or rash.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Metoprolol Succinate ER?
Tell your doctor about all your current medicines. Many drugs can affect Metoprolol Succinate ER, especially:
any other heart or blood pressure medications;
This list is not complete and many other drugs may affect Metoprolol Succinate ER. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Metoprolol is not likely to cause weight gain. However, weight gain can be a warning sign that heart failure is getting worse. If you are taking metoprolol for heart failure, tell your doctor right away if you gain weight suddenly. This weight gain is due to extra fluid in the body that may cause swelling in the feet, ankles, legs and belly. The fluid builds up because the heart isn’t working as well as it should.
Yes, metoprolol causes the blood vessels to relax, which helps to lower blood pressure. If you are prescribed metoprolol for high blood pressure, your doctor may ask you to check your blood pressure regularly at home with an automatic, cuff-style device that goes around your upper arm. Keeping track of your blood pressure at home is one way to help your doctor know if the prescribed dosage of metoprolol is working for you.
When you take metoprolol depends on which salt form is prescribed.
- Metoprolol tartrate is usually taken twice daily, so it may be taken in the morning then at night.
- Metoprolol succinate is taken once daily, so it may be taken either morning or night.
- Both forms are usually taken with or immediately after a meal.
Follow your health care provider’s directions for when to take metoprolol.
Research has suggested that taking your blood pressure medication at night instead of in the morning can provide better blood pressure control at night without compromising daytime blood pressure control and reduce your overall risk of dying because of cardiovascular disease by 45%. Continue reading
Metoprolol is available as two different salts: metoprolol tartrate and metoprolol succinate.
The main difference between metoprolol tartrate and metoprolol succinate is that metoprolol tartrate is only available as an immediate-release tablet which means it must be taken several times per day, whereas metoprolol succinate is an extended-release tablet that can be taken once a day. As a result, there are differences in the dosages and indications for both metoprolol tartrate and metoprolol succinate and they are not considered interchangeable. Continue reading
The half life of Metoprolol is between 3 and 7 hours. This is the time it takes for the drug levels in your plasma to reduce by half.
For a drug to be totally eliminated from your system it takes around 5.5 times the half life. As an estimate then, after taking a dose of Metoprolol it should be out of your system within 16.5 to 38.5 hours. Continue reading
How long it takes metoprolol to work depends on what form is given and what condition is being treated. Effects on heart rate can be seen within one hour after taking metoprolol tartrate tablets and within 20 minutes after the intravenous form is given. The onset of action of metoprolol succinate is similar to metoprolol tartrate. Continue reading
Metoprolol succinate and metoprolol tartrate contain the same active drug, metoprolol. The only difference is the salt form. Similar side effects may occur. Continue reading
No, metoprolol is not a blood thinner. It works to relax blood vessels and slow heart rate. Continue reading
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Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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