Generic Name: paliperidone (injection) (PAL ee PER i DONE)
Brand Name: Invega Sustenna, Invega Trinza
What is Invega Sustenna?
Invega Sustenna may also be used for purposes not listed in this medication guide.
Invega Sustenna is not approved for use in older adults with dementia-related conditions.
Before taking this medicine
Invega Sustenna may increase the risk of death in older adults with dementia-related conditions and is not approved for this use.
High doses or long-term use of paliperidone can cause a serious movement disorder that may not be reversible. The longer you use Invega Sustenna, the more likely you are to develop this disorder, especially if you are a woman or an older adult.
Before you receive your first injection, tell your doctor if you have never taken oral (by mouth) Invega Sustenna or risperidone.
Tell your doctor if you have ever had:
heart problems, or a heart attack;
long QT syndrome (in you or a family member);
high or low blood pressure, or fainting spells;
low white blood cell (WBC) counts;
a serious neurologic disorder caused by taking an antipsychotic medicine;
uncontrolled muscle movements in your face;
liver or kidney disease;
an electrolyte imbalance (such as low levels of potassium or magnesium in your blood);
diabetes (Invega Sustenna may raise your blood sugar); or
Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.
Using antipsychotic medicine in the last 3 months of pregnancy may cause breathing problems, feeding problems, or withdrawal symptoms in the newborn. However, you may have withdrawal symptoms or other problems if you stop using your medicine during pregnancy. If you get pregnant, tell your doctor right away. Do not stop using Invega Sustenna without your doctor's advice.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of paliperidone on the baby.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
Invega Sustenna is not approved for use by anyone younger than 18 years old.
How is Invega Sustenna given?
Invega Sustenna is injected into a muscle. A healthcare provider will give you this injection.
Invega Sustenna is usually given only once per month, but the first two doses are given 1 week apart. Invega Trinza is usually given once every 3 months, after you have used Invega Sustenna for at least 4 months in a row.
Follow your doctor's dosing instructions very carefully. Get your Invega Sustennas regularly to get the most benefit.
Your doctor will need to check your progress while you are using Invega Sustenna.
What happens if I miss a dose?
Call your doctor for instructions if you miss an appointment for your Invega Sustenna.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while using Invega Sustenna?
Avoid drinking alcohol. Dangerous side effects could occur.
While you are using Invega Sustenna, you may be more sensitive to very hot conditions. Avoid becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise.
Avoid driving or hazardous activity until you know how Invega Sustenna will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.
Invega Sustenna side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Tell your doctor right away if you have any of these signs of a serious movement disorder:
tremors or shaking in your arms or legs;
uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); or
any new or unusual muscle movements you cannot control.
Call your doctor at once if you have:
fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);
a seizure (convulsions);
breast swelling (in women or men), nipple discharge;
changes in menstrual periods;
impotence, or penis erection that is painful or lasts 4 hours or longer;
fever, chills, sore throat, mouth sores, feeling light-headed;
high blood sugar--increased thirst, increased urination, hunger, fruity breath odor; or
severe nervous system reaction--very stiff (rigid) muscles, high fever, fast or pounding heartbeats, fainting.
Common side effects may include:
cold symptoms such as stuffy nose, sneezing, sore throat;
feeling restless or anxious;
muscle stiffness, tremors or shaking;
uncontrolled muscle movements, trouble with walking, balance, or speech;
abnormal movements of your eyes;
fast heart rate; or
pain or tenderness where the medicine was injected.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Invega Sustenna?
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
Many drugs can affect Invega Sustenna. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Copyright 1996-2018 Cerner Multum, Inc. Version: 3.01.
More about Invega Sustenna (paliperidone)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- 84 Reviews
- Drug class: atypical antipsychotics
- FDA Alerts (3)
- FDA Approval History
Other brands: Invega Trinza