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In the US, Triprolidine (triprolidine systemic) is a member of the drug class antihistamines and is used to treat Allergic Rhinitis, Allergic Urticaria, Allergies, Conjunctivitis - Allergic, Eye Redness/Itching and Rhinorrhea.

US matches:



ATC (Anatomical Therapeutic Chemical Classification)


CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Categories

Antiallergic agent

Histamine H₁-receptor antagonist (H₁-antihistaminic)

Chemical Names

trans-1-(pyrid-2-yl)-3-pyrrolidino-1-p-tolylprop-1-ene (WHO)

Pyridine, 2-[1-(4-metylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-, (E)-

Foreign Names

  • Triprolidinum (Latin)
  • Triprolidin (German)
  • Triprolidine (French)
  • Tripolidina (Spanish)

Generic Names

Brand Names

  • Actifed (Triprolidine and Pseudoephedrine)
    GlaxoSmithKline, Egypt; GlaxoSmithKline, Lebanon; Johnson & Johnson, Italy; Teriak, Tunisia; Wellcome Limited, Bosnia & Herzegowina
  • Actifed composto (Triprolidine and Pseudoephedrine, + Dextromethorphan)
    Johnson & Johnson, Italy
  • Actigrip (Triprolidine and Pseudoephedrine, + Paracetamol)
    Johnson & Johnson, Italy
  • Coldrin (Triprolidine and Pseudoephedrine)
    NPI, Oman
  • Histafed (Triprolidine and Pseudoephedrine)
    Tabuk Pharmaceutical, Oman
  • Histarhine (Triprolidine and Pseudoephedrine)
    Amriya, Egypt; Amriya, Oman
  • Rinasek (Triprolidine and Pseudoephedrine)
    Hemofarm, Bosnia & Herzegowina
  • Sedofan (Triprolidine and Pseudoephedrine)
    Julphar, Lebanon
  • Sinifed (Triprolidine and Pseudoephedrine)
    Sinil Pharmaceutical Co Ltd., Hong Kong
  • Trifed (Triprolidine and Pseudoephedrine)
    Al Hikma, Oman
  • VanaHist PD
    GM Pharmaceuticals, United States
  • Acatar (Triprolidine and Pseudoephedrine hydrochloride)
    US Pharmacia, Poland
  • Actidil
    Glaxo, Pakistan
  • Actifed (Triprolidine and Pseudoephedrine, + Codeine)
    GlaxoSmithKline, Hong Kong
  • Actifed (Triprolidine and Pseudoephedrine, + Dextromethorphan)
    McNeil, Poland
  • Actifed (Triprolidine and Pseudoephedrine)
    Aspen, Georgia; Glaxo, Pakistan; Glaxo Wellcome, Indonesia; Glaxo Wellcome, Romania; GlaxoSmithKline, India; GlaxoSmithKline, Kenya; GlaxoSmithKline, Malta; GlaxoSmithKline, Malaysia; GlaxoSmithKline, Peru; GlaxoSmithKline, Singapore; GlaxoSmithKline, South Africa; GSK, Turkey; Johnson & Johnson, Latvia; Johnson & Johnson, Portugal; McNeil, Estonia; McNeil, Ireland; McNeil, Lithuania; Samil, South Korea
  • Actifed Compound (Triprolidine and Codeine, + Pseudoephedrine)
    GlaxoSmithKline, Singapore
  • Actifed DM (Triprolidine and Dextromethorphan, + Pseudoephedrine)
    GlaxoSmithKline, Singapore
  • Actifed Expectorant (Triprolidine and Pseudoephedrine, + Guaifenesin)
    GlaxoSmithKline, Malaysia; GlaxoSmithKline, Singapore
  • Actifed Rhume (Triprolidine and Pseudoephedrine, + Paracetamol)
    Johnson & Johnson, France
  • Actifed-DM (Triprolidine and Dextromethorphan)
    GlaxoSmithKline, India
  • Actifedrin
    Farmoquimica, Brazil
  • Actifedrin (Triprolidine and Pseudoephedrine)
    GlaxoSmithKline, Chile
  • Actihist (Triprolidine and Pseudoephedrine)
    Hovid, Hong Kong
  • Actirin (Triprolidine and Pseudoephedrine)
    Sinphar, Taiwan
  • ACTI-trin (Triprolidine and Pseudoephedrine, + Dextromethorphan)
    Hasco-Lek, Poland
  • Alerfed (Triprolidine and Pseudoephedrine)
    Guardian Pharmatama, Indonesia
  • Altafed (Triprolidine and Pseudoephedrine)
    Altaire, United States
  • Anmin
    AND, Taiwan
  • Antifort (Triprolidine and Pseudoephedrine)
    Christo, Hong Kong
  • Axcel Tridine (Triprolidine and Pseudoephedrine)
    Kotra Pharma, Malaysia
  • Becandin (Triprolidine and Pseudoephedrine)
    Root, Taiwan
  • Benylin Children's Cough & Colds (Triprolidine and Dextromethorphan (pediatric))
    McNeil, Ireland
  • Benylin Dual Action Dry (Triprolidine and Dextromethorphan, + Pseudoephedrine)
    McNeil, Ireland
  • Besuton (Triprolidine and Pseudoephedrine)
    Ying Yuan, Taiwan
  • Betafed (Triprolidine and Pseudoephedrine)
    Be-Tabs Pharmaceuticals, South Africa
  • CoActifed (Triprolidine and Pseudoephedrine, + Codeine)
    GlaxoSmithKline, Canada
  • CoActifed Expectorant (Triprolidine and Pseudoephedrine, + Codeine, + Guaifenesin)
    GlaxoSmithKline, Canada
  • Cough-EN (Triprolidine and Dextromethorphan, + Pseudoephedrine)
    Xepa-Soul Pattinson, Malaysia
  • Cough-EN RX (Triprolidine and Dextromethorphan, + Phenylephrine)
    Xepa-Soul Pattinson, Malaysia
  • Covan (Triprolidine and Codeine, + Pseudoephedrine)
    Pharmascience, Canada
  • Crofed (Triprolidine and Pseudoephedrine)
    Coronet Crown, Indonesia
  • Decofed (Triprolidine and Pseudoephedrine)
    Goldex, South Africa
  • Decondine (Triprolidine and Pseudoephedrine)
    Sunward Pharmaceutical, Singapore
  • Dinaxil (Triprolidine and Pseudoephedrine)
    Tecnifar, Portugal
  • Ed A-Hist PSE (Triprolidine and Pseudoephedrine)
    Edwards, United States
  • Eflin (Triprolidine and Pseudoephedrine)
    Meprofarm, Indonesia
  • Entre-Hist PSE (Triprolidine and Pseudoephedrine)
    Acella, United States
  • Eugen (Triprolidine and Pseudoephedrine)
    Yu Sheng, Taiwan
  • Exos (Triprolidine and Pseudoephedrine)
    Hankook Korus Pharm Co Ltd, Hong Kong
  • Fedac (Triprolidine and Pseudoephedrine)
    DHA, Hong Kong; DHA, Malaysia; DHA, Singapore
  • Fedac Compound (Triprolidine and Pseudoephedrine, + Codeine)
    DHA, Hong Kong; DHA, Singapore
  • Flu-Care (Triprolidine and Pseudoephedrine)
    Riyadh Pharma, Oman
  • Flutrop (Triprolidine and Pseudoephedrine)
    Tropica, Indonesia
  • Frenos (Triprolidine and Pseudoephedrine)
    Opsonin, Bangladesh
  • Genac (Triprolidine and Pseudoephedrine)
    Ivax, United States
  • Grafed (Triprolidine and Pseudoephedrine)
    Gracia Pharmindo, Indonesia
  • Histafed (Triprolidine and Pseudoephedrine)
    Trima, Israel
  • Histamine (Triprolidine and Pseudoephedrine)
    Trima, Israel
  • Hist-PSE (Triprolidine and Pseudoephedrine)
    Cypress, United States
  • Lapifed (Triprolidine and Pseudoephedrine)
    Lapi Laboratories, Indonesia
  • Librofed (Triprolidine and Pseudoephedrine)
    Kalbe, Indonesia
  • Maldex Compuesto (Triprolidine and Dextromethorphan, + Guaifenesin, + Pseudoephedrine)
    Markos, Peru
  • Medofed (Triprolidine and Pseudoephedrine)
    Medochemie, Malta
  • Mertisal (Triprolidine and Pseudoephedrine)
    Mersifarma, Indonesia
  • Multi-Action Actifed (Triprolidine and Pseudoephedrine)
    AlphaFarma, Malta; McNeil Products, United Kingdom
  • Multi-Action Actifed Chesty Coughs (Triprolidine and Guaifenesin, + Pseudoephedrine)
    McNeil Products, United Kingdom
  • Multi-Action Actifed Dry Coughs (Triprolidine and Dextromethorphan, + Pseudoephedrine)
    McNeil Products, United Kingdom
  • Nasafed (Triprolidine and Pseudoephedrine)
    Medikon, Indonesia
  • Neo Protifed (Triprolidine and Pseudoephedrine)
    Graha, Indonesia
  • Neocold (Triprolidine and Pseudoephedrine)
    Neopharma, Oman
  • Nichofed (Triprolidine and Pseudoephedrine)
    Nicholas Laboratories, Indonesia
  • Nosetop (Triprolidine and Pseudoephedrine)
    Kolmar Pharma, Hong Kong
  • Nostel (Triprolidine and Pseudoephedrine)
    Pyridam Farma, Indonesia
  • Pabron Cough & Sinus (Triprolidine and Pseudoephedrine, + Guaifenesin)
    Taisho Pahramceuticals, Malaysia
  • Pabron Cough-D (Triprolidine and Dextromethorphan, + Pseudoephedrine)
    Taisho Pahramceuticals, Malaysia
  • Peace (Triprolidine and Pseudoephedrine)
    Standard, Taiwan
  • Pedolin (Triprolidine and Pseudoephedrine)
    Standard, Taiwan
  • Peesu (Triprolidine and Pseudoephedrine)
    Kojar, Taiwan
  • Pharmaniaga Pseudoephedrine T (Triprolidine and Pseudoephedrine)
    Pharmaniaga, Malaysia
  • Pisu (Triprolidine and Pseudoephedrine)
    Jen Sheng, Taiwan
  • Prohist CF (Triprolidine and Clofedanol)
    Poly Pharmaceuticals, United States
  • Prolifed (Triprolidine and Pseudoephedrine)
    Quality Pharm, Hong Kong
  • Promedols
    Kalceks, Georgia
  • Protifed (Triprolidine and Pseudoephedrin)
    Graha, Indonesia
  • Pseu (Triprolidine and Pseudoephedrine)
    Kojar, Taiwan
  • Quantidex (Triprolidine and Pseudoephedrine)
    Ifars, Indonesia
  • ratio-Cotridin (Triprolidine and Codeine, + Pseudoephedrine)
    Teva Canada, Canada
  • Relizine (Triprolidine and Pseudoephedrine)
    Shou Chan, Taiwan
  • Rhinopront Kombi (Triprolidine and Pseudoephedrine)
    McNeil, Germany
  • Rinafed (Triprolidine and Pseudoephedrine)
    Pharmaniaga, Vietnam
  • Rinasek (Triprolidine and Pseudoephedrine)
    Hemofarm, Serbia
  • Rinofed (Triprolidine and Pseudoephedrine)
    JPI - Jazeera, Oman
  • Sedofan (Triprolidine and Pseudoephedrine)
    Julphar, Oman
  • Silafed (Triprolidine and Pseudoephedrine)
    Silarx, United States
  • Spiz (Triprolidine and Pseudoephedrine)
    Taiwan Biotech, Taiwan
  • Tosumin (Triprolidine and Pseudoephedrine)
    Weidar, Taiwan
  • Tremenza (Triprolidine and Pseudoephedrine)
    Sanbe, Indonesia
  • Trifed (Triprolidine and Pseudoephedrine)
    Hikma, Slovakia; Interbat, Indonesia; Norris Medicines, Georgia
  • Trifedrin (Triprolidine and Pseudoephedrine)
    Otto Pharmaceutical, Indonesia
  • Unifed (Triprolidine and Pseudoepinephrine)
    United Pharmaceutical, Oman
  • Uni-Fedra (Triprolidine and Pseudoephedrine, + Codeine)
    Universal Pharm, Hong Kong
  • Valved (Triprolidine and Pseudoephedrine)
    Global Multi Pharmalab, Indonesia
  • Venen
    Sato Seiyaku, Japan
  • Zentra (Triprolidine and Pseudoephedrine)
    Zenith Pharmaceuticals, Indonesia


BANBritish Approved Name
BANMBritish Approved Name (Modified)
DCFDénomination Commune Française
DCITDenominazione Comune Italiana
JANJapanese Accepted Name
OSOfficial Synonym
PHPharmacopoeia Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
WHOWorld Health Organization

Further information on drug naming conventions: International Nonproprietary Names.

Important Notice: The international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Further information

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