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Otrivin (xylometazoline nasal) Drug Interactions

A total of 67 drugs are known to interact with Otrivin (xylometazoline nasal).

  • 1 major drug interaction
  • 66 moderate drug interactions

Show all medications in the database that may interact with Otrivin (xylometazoline nasal).

Check for interactions with Otrivin (xylometazoline nasal)

Type in a drug name and select a drug from the list.

Common medications checked in combination with Otrivin (xylometazoline nasal)

  • aloe vera
  • amoxicillin (Amoxil, Trimox, Moxilin, Apo-Amoxi, Amoxicot, Moxatag, DisperMox, Wymox, Biomox)
  • aspirin (Aspir 81, Ecotrin, Acetylsalicylic Acid, Aspirin Low Strength, Aspir-Low, Bayer Aspirin, Ecotrin Adult Low Strength, Ascriptin, Fasprin, Arthritis Pain, Low Dose ASA, Aspiritab, Bufferin, Durlaza, Aspirin Lite Coat, Aspirtab, Halfprin, Bayer Children's Aspirin, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Easprin, Aspergum, Buffered Aspirin, Ascriptin Enteric, Acuprin 81, Miniprin, Bayer Aspirin Regimen, St. Joseph 81 mg Chewable Aspirin, Empirin, Ecotrin Maximum Strength, St. Joseph Aspirin, Ecpirin, Bayer Women's Aspirin With Calcium, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Aspi-Cor, Bufferin Low Dose, Medi-Seltzer, Sloprin, ZORprin, Bayer Aspirin Extra Strength Plus, Buffex, Entercote, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Bufferin Extra Strength, Therapy Bayer, Stanback Analgesic, Norwich Aspirin, Zero-Order Release, YSP Aspirin, Migralex, Heartline, Bayer Advanced Aspirin, Buffasal)
  • Ativan (lorazepam)
  • ceftriaxone (Rocephin)
  • cetirizine (Zyrtec, Aller-Tec, Zyrtec Hives, All Day Allergy, Children's Allergy Relief, PediaCare Children's 24-Hour Allergy, All Day Allergy Children's, Equate Allergy Relief, Children's Zyrtec, Alleroff, Aller-Tec Children's)
  • Claritin (loratadine)
  • diphenhydramine (Benadryl, Banophen, Benadryl Allergy, ZzzQuil, Unisom SleepGels, Diphenhist, Sleep, Dicopanol, Diphenadryl, Sominex, Diphen, Diphedryl, Hydramine, Allermax, Nytol, Benadryl Children's Allergy, Diphenydramine Quick Melt, Pharbedryl, Buckley's Bedtime, Hyrexin, Diphen Cough, DPH, Allergia-C, Q-Dryl, Sleep-Eze-3, Valu-Dryl, Diphenyl, Beldin, Sleep-ettes, Diphendryl, Q-Dryl A/F, Tranquil Nighttime Sleep Aid, Dormin, Sleepwell 2-nite, Snooze Fast, Sominex Maximum Strength Caplet, Unisom SleepMinis, Unisom Liquid, Triaminic Thin Strips Allergy, ConRx Allergy, Hydramine Cough Syrup, Bydramine, 40 Winks, Diphen AF, Aler-Dryl, Benahist-10, Benahist-50, Benoject-50, Calm-Aid, Genahist, Alka-Seltzer Plus Allergy, Aller-G-Time, Sleep Tab II, Sleep Tabs, Somnicaps, Nytol QuickCaps, Total Allergy, Trux-adryl, Altaryl, Triaminic Thin Strips Cough & Runny Nose, Belix, Vicks QlearQuil Nighttime Allergy Relief, Siladryl, Siladryl DAS, Siladyl SA, Silphen Cough, Tusstat, Diphenylin, Hydramine Compound, Pardryl, Quenalin, Nervine, Nu-Med, Nytol Caplet, Compoz Nighttime Sleep Aid, Sleepinal, Help I Can't Sleep, Twilite, Banaril, Aler-Tab, Siladryl Allergy, Theraflu Thin Strips Multi Symptom, Sleep-ettes D, Uni-Tann, Diphenmax, Nightime Sleepaid, Ben-Tann, Dytan, Vanamine PD, Histaprin, Z-Sleep, Unisom SleepMelts, PediaCare Children's Allergy, Truxadryl, Simply Sleep, Complete Allergy Relief, Dytuss, Miles Nervine, Scot-Tussin Allergy)
  • folic acid (Folvite, Folacin-800, FaLessa, FA-8)
  • ibuprofen (Advil, Motrin, IBU, Proprinal, Advil Liqui-Gels, Motrin IB, IBU-200, Nuprin, Children's Motrin, Motrin Migraine Pain, Advil Migraine, Caldolor, Ibuprofen PMR, Advil Children's, Addaprin, NeoProfen, Advil Infant's Concentrated Drops, A-G Profen, Motrin Childrens, Childrens Ibuprofen Berry, Ibu-6, Ibu-8, Motrin Infant Drops, Ibu-Tab, Rufen, Genpril, Haltran, Menadol, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Actiprofen, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Cap-Profen, Motrin Pediatric, Advil Film-Coated)
  • metronidazole (Flagyl, Flagyl IV, Metro, Metro IV, Flagyl 375, Protostat, Metryl, Flagyl ER)
  • naproxen (Aleve, Naprosyn, Naproxen Sodium DS, Anaprox, Naprelan, Anaprox-DS, Flanax Pain Reliever, Leader Naproxen Sodium, EC-Naprosyn, Aflaxen, All Day Pain Relief, Comfort Pac with Naproxen, Pamprin All Day Relief, Midol Extended Relief, All Day Relief)
  • Nasonex (mometasone nasal)
  • Norvasc (amlodipine)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • ondansetron (Zofran, Zofran ODT, Zuplenz)
  • Panadol (acetaminophen)
  • pantoprazole (Protonix, Protonix IV)
  • Paracetamol (acetaminophen)
  • Synthroid (levothyroxine)
  • Ventolin (albuterol)
  • Vitamin C (ascorbic acid)
  • Vitamin D3 (cholecalciferol)
  • Zyrtec (cetirizine)

Otrivin (xylometazoline nasal) disease interactions

There are 3 disease interactions with Otrivin (xylometazoline nasal) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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