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Otrivin Side Effects

Generic name: xylometazoline nasal

Note: This document contains side effect information about xylometazoline nasal. Some of the dosage forms listed on this page may not apply to the brand name Otrivin.

Applies to xylometazoline nasal: nasal spray


Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Although the risk of serious side effects is low when xylometazoline is used in the nose, side effects can occur if the medicine is absorbed into your bloodstream.

Stop using this medicine and call your doctor at once if you have:

  • blurred vision;

  • headache, dizziness, nervousness;

  • fast or pounding heartbeats;

  • a light-headed feeling, like you might pass out;

  • wheezing, feeling short of breath; or

  • worsening symptoms.

Common side effects may include:

  • dryness, burning, or stinging inside your nose;

  • sneezing; or

  • runny nose.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Medically reviewed by Last updated on Nov 8, 2020.

More about Otrivin (xylometazoline nasal)

Consumer resources

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.