Drug Interactions between eszopiclone and ibuprofen
This report displays the potential drug interactions for the following 2 drugs:
- eszopiclone
- ibuprofen
Interactions between your drugs
No interactions were found between eszopiclone and ibuprofen. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
eszopiclone
A total of 375 drugs are known to interact with eszopiclone.
- Eszopiclone is in the drug class miscellaneous anxiolytics, sedatives and hypnotics.
- Eszopiclone is used to treat Insomnia.
ibuprofen
A total of 397 drugs are known to interact with ibuprofen.
- Ibuprofen is in the drug class Nonsteroidal anti-inflammatory drugs.
-
Ibuprofen is used to treat the following conditions:
- Aseptic Necrosis
- Back Pain
- Chronic Myofascial Pain
- Chronic Pain
- Costochondritis
- Diffuse Idiopathic Skeletal Hyperostosis
- Dysautonomia
- Eustachian Tube Dysfunction
- Fever
- Frozen Shoulder
- Gout, Acute
- Headache
- Herniated Disk (off-label)
- Juvenile Rheumatoid Arthritis
- Migraine
- Muscle Pain
- Neck Pain
- Osteoarthritis
- Pain
- Pain/Fever
- Patent Ductus Arteriosus
- Period Pain
- Plantar Fasciitis
- Polymyalgia Rheumatica
- Radiculopathy
- Rheumatoid Arthritis
- Sciatica
- Spondylolisthesis
- Temporomandibular Joint Disorder
- Toothache
- Transverse Myelitis
Drug and food interactions
eszopiclone food
Applies to: eszopiclone
GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of zopiclone and eszopiclone. Use in combination may result in additive central nervous system depression and/or impairment of judgment, thinking, and psychomotor skills.
ADJUST DOSING INTERVAL: Administration of eszopiclone (the S-enantiomer of zopiclone) with or immediately after a high-fat/heavy meal may delay the onset of hypnotic effects. In healthy adults, administration of a 3 mg dose of eszopiclone after a high-fat meal decreased the mean peak plasma drug concentration (Cmax) by 21% and delayed the time to reach peak plasma drug concentration (Tmax) by approximately 1 hour. Theoretically, this interaction should also affect racemic zopiclone.
MANAGEMENT: Patients receiving zopiclone or eszopiclone should be advised to avoid consumption of alcohol. For faster sleep onset, eszopiclone and zopiclone should not be administered with or immediately after a high-fat/heavy meal.
References
- (2004) "Product Information. Lunesta (eszopiclone)." Sepracor Inc
- Cerner Multum, Inc. "UK Summary of Product Characteristics."
ibuprofen food
Applies to: ibuprofen
GENERALLY AVOID: The concurrent use of aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) and ethanol may lead to gastrointestinal (GI) blood loss. The mechanism may be due to a combined local effect as well as inhibition of prostaglandins leading to decreased integrity of the GI lining.
MANAGEMENT: Patients should be counseled on this potential interaction and advised to refrain from alcohol consumption while taking aspirin or NSAIDs.
References
- (2002) "Product Information. Motrin (ibuprofen)." Pharmacia and Upjohn
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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