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Dupixent (dupilumab) Drug Interactions

A total of 71 drugs are known to interact with Dupixent (dupilumab).

  • 31 major drug interactions
  • 25 moderate drug interactions
  • 15 minor drug interactions

Show all medications in the database that may interact with Dupixent (dupilumab).

Check for interactions

Type in a drug name to check for interactions with Dupixent (dupilumab).

Most frequently checked interactions

View interaction reports for Dupixent (dupilumab) and the medicines listed below.

  • Advair Diskus (fluticasone / salmeterol)
  • amoxicillin (Amoxil, Trimox, Apo-Amoxi, Amoxicot, Moxatag, DisperMox, Biomox, Wymox, Moxilin)
  • cetirizine (Zyrtec, Aller-Tec, Children's Zyrtec, Equate Allergy Relief, Children's Allergy Relief, Aller-Tec Children's, PediaCare Children's 24-Hour Allergy, All Day Allergy Children's, All Day Allergy, Zyrtec Hives, Alleroff)
  • clonazepam (Klonopin, Klonopin Wafer)
  • cyclosporine (Neoral, Sandimmune, Gengraf)
  • Cymbalta (duloxetine)
  • doxycycline (Vibramycin, Oracea, Doxy 100, Monodox, Doryx, Targadox, Vibra-Tabs, Adoxa, Acticlate, Morgidox, Periostat, Doxy-Caps, Uracil, Adoxa TT, Mondoxyne NL, Doxy 200, Doxy-D, Oraxyl, Alodox, Adoxa Pak, Avidoxy, Adoxa CK, Ocudox, LymePak, NicAzel Doxy, Doxy-Lemmon, Doryx MPC)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • Humira (adalimumab)
  • hydroxyzine (Vistaril, Atarax, Hyzine, Vistazine, Rezine)
  • ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Motrin IB, Proprinal, Advil Children's, Caldolor, Children's Motrin, Childrens Ibuprofen Berry, Motrin Childrens, Rufen, Ibuprofen PMR, Ibu-8, Motrin Pediatric, Menadol, Nuprin, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, Advil Migraine, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, NeoProfen, Ibu-Tab, Genpril, Haltran, IBU-200, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Actiprofen, Addaprin, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, Motrin Junior Strength, Motrin Infant Drops, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Levothroid, Eltroxin, Levothyrox, Euthyrox, Unithroid, L Thyroxine Roche, Levo-T, Oroxine, Eutroxsig, Novothyrox, Tirosint-Sol, Levotabs, Levotec, Evotrox)
  • Lyrica (pregabalin)
  • metformin (Glucophage, Glumetza, Glucophage XR, Fortamet, Riomet)
  • montelukast (Singulair)
  • Nexium (esomeprazole)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • prednisone (Deltasone, Rayos, Sterapred, Prednicot, Meticorten, Sterapred DS, Liquid Pred, Orasone, Prednicen-M)
  • Singulair (montelukast)
  • Vitamin D3 (cholecalciferol)
  • vitamin e (Alpha E, Aquasol E, Aqua-E, Aqua Gem-E, E-600, E-Gems, E Pherol, Amino-Opti-E, Vita-Plus E Natural, Nutr-E-Sol, E-400 Clear, Centrum Singles-Vitamin E, Aquavite-E, E-Max-1000)
  • Zyrtec (cetirizine)

Dupixent (dupilumab) disease interactions

There are 2 disease interactions with Dupixent (dupilumab) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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