Dupixent (dupilumab) Disease Interactions
There are 3 disease interactions with Dupixent (dupilumab):
Interleukin inhibitors (applies to Dupixent) immunization
Major Potential Hazard, Moderate plausibility. Applicable conditions: Vaccination
Patients requiring non-live vaccination during a course of therapy with interleukin inhibitors may not be protected from the vaccine as the immune response might not be sufficient to prevent the disease. It is recommended to be up-to-date with all required immunizations, as recommended by current immunization guidelines, before initiating therapy with these agents. Patients treated with interleukin inhibitors should not receive live vaccines due to potentially increased risk of infections. Caution is advised when administering live vaccines to household contacts of patients receiving interleukin inhibitors because of the potential risk for shedding from the household contact and transmission to patient.
Dupilumab (applies to Dupixent) helminth infections
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Infection - Bacterial/Fungal/Protozoal/Viral
Patients with preexisting-existing helminth infections should be treated prior to therapy with dupilumab. It is recommended to discontinue treatment with dupilumab if patients become infected while on treatment and if they are not responding to treatment. Discontinue treatment with dupilumab until the infection resolves.
Dupilumab (applies to Dupixent) visual defects
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Visual Defect/Disturbance
Conjunctivitis and keratitis may occur while on treatment with dupilumab. Care should be exercised when using this agent in patients with visual defects. Patients should be closely monitored for new onset or worsening eye symptoms.
Dupixent (dupilumab) drug interactions
There are 66 drug interactions with Dupixent (dupilumab)
More about Dupixent (dupilumab)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Patient Tips
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Español
- 272 Reviews
- Drug class: interleukin inhibitors
- FDA Approval History
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
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