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Dupixent Disease Interactions

There are 2 disease interactions with Dupixent (dupilumab).

Moderate

Dupilumab (applies to Dupixent) helminth infections

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Infection - Bacterial/Fungal/Protozoal/Viral

Patients with preexisting helminth infections should be treated prior to therapy with dupilumab. If patients become infected while receiving dupilumab and do not respond to anthelminthic treatment, dupilumab should be discontinued until the infection resolves.

References

  1. (2022) "Product Information. Dupixent Pre-filled Syringe (dupilumab)." sanofi-aventis, SUPPL-46
Moderate

Dupilumab (applies to Dupixent) visual defects

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Visual Defect/Disturbance

Conjunctivitis and keratitis adverse reactions have been reported with dupilumab. Care should be exercised when using this agent in patients with visual defects. Patients should be advised to report new onset or worsening eye symptoms to their health care provider.

References

  1. (2022) "Product Information. Dupixent Pre-filled Syringe (dupilumab)." sanofi-aventis, SUPPL-46

Dupixent drug interactions

There are 76 drug interactions with Dupixent (dupilumab).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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