Generic Name: tildrakizumab (til-dra-KIZ-ue-mab - asmn)
Medically reviewed by Drugs.com. Last updated on Feb 20, 2021.
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
Therapeutic Class: Antipsoriatic
Pharmacologic Class: Tildrakizumab
Uses for tildrakizumab-asmn
Tildrakizumab-asmn injection is used to treat moderate to severe plaque psoriasis in patients who may benefit from receiving phototherapy (ultraviolet light treatment) or other treatments. Plaque psoriasis is a skin disease with red patches and white scales that do not go away.
Tildrakizumab-asmn is to be given only by or under the direct supervision of your doctor.
Before using tildrakizumab-asmn
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For tildrakizumab-asmn, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to tildrakizumab-asmn or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of tildrakizumab-asmn injection in the pediatric population. Safety and efficacy have not been established.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of tildrakizumab-asmn injection in the elderly.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving tildrakizumab-asmn, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using tildrakizumab-asmn with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Adenovirus Vaccine
- Bacillus of Calmette and Guerin Vaccine, Live
- Cholera Vaccine, Live
- Dengue Tetravalent Vaccine, Live
- Influenza Virus Vaccine, Live
- Measles Virus Vaccine, Live
- Mumps Virus Vaccine, Live
- Poliovirus Vaccine, Live
- Rotavirus Vaccine, Live
- Rubella Virus Vaccine, Live
- Smallpox Vaccine
- Typhoid Vaccine
- Varicella Virus Vaccine, Live
- Yellow Fever Vaccine
- Zoster Vaccine, Live
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other medical problems
The presence of other medical problems may affect the use of tildrakizumab-asmn. Make sure you tell your doctor if you have any other medical problems, especially:
- Infection, or history of—Use is not recommended for patients with an active infection, including tuberculosis, until properly treated. Caution should be used if you have a chronic infection or history of a recurring infection.
- Tuberculosis infection, inactive—Should be treated first before starting treatment with tildrakizumab-asmn.
Proper use of tildrakizumab-asmn
A nurse or other trained health professional will give you tildrakizumab-asmn in a medical facility. It is given as a shot under your skin (eg, stomach, thighs, upper arm) at weeks 0 and 4 and every 12 weeks thereafter.
Precautions while using tildrakizumab-asmn
It is very important that your doctor check your progress at regular visits to make sure that tildrakizumab-asmn is working properly and to check for unwanted effects.
You will need to have a skin test for tuberculosis before you start receiving tildrakizumab-asmn. Tell your doctor if you or anyone in your home has ever had a positive reaction to a tuberculosis skin test.
Tildrakizumab-asmn may cause serious allergic reactions, including angioedema, which can be life-threatening and requires immediate medical attention. Tell your doctor right away if you have a rash, itching, or large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals after receiving tildrakizumab-asmn.
It is important to check with your doctor if you have any symptoms of an infection, such as fever or chills, cough or hoarseness, lower back or side pain, painful or difficult urination.
Do not have any live vaccines (immunizations) while you are being treated with tildrakizumab-asmn. Ask your doctor if you have any concerns.
Tildrakizumab-asmn side effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
- Body aches or pain
- difficulty in breathing
- ear congestion
- loss of voice
- nasal congestion
- runny nose
- sore throat
- unusual tiredness or weakness
Incidence not known
- Itching skin
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
- pain in the arms and legs
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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More about tildrakizumab
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- En Español
- 4 Reviews
- Drug class: interleukin inhibitors
- Other brands
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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.