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Medications for Onychomycosis, Toenail

Other names: Fungal Infection, Toenail; Infection, Fungal, Toenail

Fungal infections of the toenails, causing thickening, roughness, and splitting, often caused by Trichophyton rubrum or T. mentagrophytes, Candida, and occasionally molds.

Drugs used to treat Onychomycosis, Toenail

The following list of medications are in some way related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
terbinafine 6.5 395 reviews for terbinafine to treat Onychomycosis, Toenail
Rx B N
Generic name:
terbinafine systemic
Brand names:
Lamisil, Terbinex
Drug class:
miscellaneous antifungals
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Lamisil 6.9 116 reviews for Lamisil to treat Onychomycosis, Toenail
Rx B N
Generic name:
terbinafine systemic
Drug class:
miscellaneous antifungals
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ciclopirox 7.4 44 reviews for ciclopirox to treat Onychomycosis, Toenail
Rx B N
Generic name:
ciclopirox topical
Brand names:
Ciclodan, Penlac, Penlac Nail Lacquer, CNL8 Nail
Drug class:
topical antifungals
For consumers:
dosage, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
fluconazole Off-label 8.1 14 reviews for fluconazole to treat Onychomycosis, Toenail
Rx C N
Generic name:
fluconazole systemic
Drug class:
azole antifungals
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Jublia 5.6 228 reviews for Jublia to treat Onychomycosis, Toenail
Rx C N
Generic name:
efinaconazole topical
Drug class:
topical antifungals
For consumers:
dosage, side effects
For professionals:
Prescribing Information
ketoconazole Off-label 10 2 reviews for ketoconazole to treat Onychomycosis, Toenail
Rx C N X
Generic name:
ketoconazole systemic
Drug class:
azole antifungals
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Ciclodan 10 1 review for Ciclodan to treat Onychomycosis, Toenail
Rx B N
Generic name:
ciclopirox topical
For consumers:
dosage, side effects
For professionals:
Prescribing Information
itraconazole 5.0 12 reviews for itraconazole to treat Onychomycosis, Toenail
Rx C N
Generic name:
itraconazole systemic
Brand name:
Sporanox
Drug class:
azole antifungals
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Penlac 4.5 2 reviews for Penlac to treat Onychomycosis, Toenail
Rx B N
Generic name:
ciclopirox topical
Drug class:
topical antifungals
For consumers:
dosage, side effects
For professionals:
Prescribing Information
Sporanox 6.8 5 reviews for Sporanox to treat Onychomycosis, Toenail
Rx C N
Generic name:
itraconazole systemic
Drug class:
azole antifungals
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Kerydin 4.4 31 reviews for Kerydin to treat Onychomycosis, Toenail
Rx C N
Generic name:
tavaborole topical
Drug class:
topical antifungals
For consumers:
dosage, side effects
For professionals:
Prescribing Information
Terbinex Rate Add review
Rx B N
Generic name:
terbinafine systemic
Drug class:
miscellaneous antifungals
For consumers:
dosage, interactions, side effects
efinaconazole 5.6 228 reviews for efinaconazole to treat Onychomycosis, Toenail
Rx C N
Generic name:
efinaconazole topical
Brand name:
Jublia
Drug class:
topical antifungals
For consumers:
dosage, side effects
For professionals:
AHFS DI Monograph
griseofulvin 1.0 4 reviews for griseofulvin to treat Onychomycosis, Toenail
Rx C N
Generic name:
griseofulvin systemic
Brand name:
Gris-PEG
Drug class:
miscellaneous antifungals
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Penlac Nail Lacquer 2.0 2 reviews for Penlac Nail Lacquer to treat Onychomycosis, Toenail
Rx B N
Generic name:
ciclopirox topical
Drug class:
topical antifungals
For consumers:
dosage, side effects
tavaborole 4.4 33 reviews for tavaborole to treat Onychomycosis, Toenail
Rx C N
Generic name:
tavaborole topical
Brand name:
Kerydin
Drug class:
topical antifungals
For consumers:
dosage, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
CNL8 Nail Rate Add review
Rx B N
Generic name:
ciclopirox topical
Drug class:
topical antifungals
For consumers:
dosage, side effects
Gris-PEG 1.0 2 reviews for Gris-PEG to treat Onychomycosis, Toenail
Rx C N
Generic name:
griseofulvin systemic
Drug class:
miscellaneous antifungals
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information

Frequently asked questions

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.