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Fluconazole for Onychomycosis, Toenail User Reviews

Brand names: Diflucan

Fluconazole has an average rating of 8.1 out of 10 from a total of 13 reviews for the off-label treatment of Onychomycosis, Toenail. 77% of reviewers reported a positive experience, while 15% reported a negative experience.

Fluconazole rating summary

8.1 average rating out of 10

13 ratings from 14 user reviews.

Compare all 18 medications used in the treatment of Onychomycosis, Toenail.

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15%
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Reviews for Fluconazole

  • mon...
  • April 14, 2009

Diflucan (fluconazole) "I had terrible toenail fungus for many years. I participated in a double-blind study of Diflucan for toenail fungus, and it was like a miracle. Month by month, the fungus disappeared. Each month, I had blood work done. There was never a change in my liver function studies. It has been 10 years, and the fungus has never reappeared."

10 / 10
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159 Report
  • Pes...
  • Taken for less than 1 month
  • October 15, 2017

"I have had toenail fungus for the last 45 years. My doctors would only give a cream to apply. While visiting friends in Ukraine, my friend suggested I use fluconazole. It is available over the counter in Ukraine. I used 50 mg, one a day for 10 days. The fungus is gone, and I have been clear for 6 months now."

10 / 10
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79 Report
  • Sta...
  • Taken for 2 to 5 years
  • February 18, 2020

"I had unsightly toenail fungus for many, many years. I didn't want to take Lamisil because of the liver side effects. My dermatologist suggested fluconazole. I took 150 mg per week. What a drug... my toenail fungus disappeared completely after around 9 months. It didn't work on one toenail, but after another round of fluconazole, that toenail healed, as well. I highly recommend fluconazole, but, of course, make sure you consult with your doctor or dermatologist first."

10 / 10
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46 Report

Frequently asked questions

  • Est...
  • April 9, 2016

"While in Costa Rica, an itchy skin condition that was developing for some time and which I did not know was fungus got worse. Went into a pharmacy and was recommended fluconazole. Within an hour, the itchiness started to subside. By the next day, there was visible improvement. By the end of the first week, chronic Athlete's foot was mostly healed, as was jock itch. Got back to the states, saw my doc, told him I wanted to continue with it to treat the nail fungus. He suggested a different drug. After a month, I stopped seeing improvement. Switched back to fluconazole. Eight years later, I have never gotten Athlete's foot again, and I had it most of my life between two particular toes. It is as if I am permanently inoculated against fungus."

10 / 10
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46 Report
  • 30y...
  • April 29, 2020

"I just started taking a medication called Afumix. I was prescribed this medication after seeing a dermatologist in GDL, MX, he sent me to have a culture done. They scraped the nail to identify the type of fungal infection. I’ve had it for over 30 years, battling athlete's foot as well. I’ve suffered with this for so many years: unsightly toenails and itchy feet. I started this medication 4 days ago and will now take 6 days off, then back on 4 days, on 6 days off. I will continue this cycle until I’m done with 16 pills. By the way, I bought this medication in Mexico for just under $100: 4 boxes with 4 pills in each box. I already have noticed that the skin on my feet feels smoother and absolutely no itchiness between my toes. It appears to be clearing the skin peeling. I will continue to update the results after I’m done with the dose. FYI, I’ve tried the Lamisil/terbinafine pills and cream, both never worked for me."

7 / 10
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24 Report

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  • Bom...
  • February 17, 2016

"I just started 100 mg, and I'd like to know how long it took to clear the infection. Is there anything else I can use in conjunction with this medicine? If anyone did and cleared their infection, can they please let me know? Thank you."

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33 Report
  • Ahm...
  • Taken for 1 to 6 months
  • June 12, 2022

"Fluconazole is an amazing medicine as it completely sorted out my fungal toenail issue. I first cut off my crooked, dry, crumbly left toenail to its root point, where I could see fresh white nail. I then started to take 150 mg fluconazole capsules in January 2022. I will now be finishing my course of 6 months at the end of this month, June 2022. I have a fresh white left toenail now, full of life and energy. The only side effect I experienced was some sleep disruption, apart from that, I was fine. If I could've sent before and after pics, then that would've been good."

9 / 10
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10 Report

More FAQ

  • rad...
  • April 21, 2016

"I took a 6-month course of fluconazole beginning in the fall of 2013 for a moderate, but long-term case of toenail fungus (both big toes). One nail is now clear and has reattached. The other is now worse, and I just completed another 6-month course. Am hoping for resolution. I'm also using Penlac on it. Lamisil (oral) made me feel awful, or I would have used it instead."

8 / 10
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24 Report
  • Mot...
  • Taken for 6 months to 1 year
  • July 13, 2014

"They gave this to my child since he got 2 toenails infected with fungus. (I think he got it on vacation.) Anyway, he was using this and it was working miracles, so definitely push the doctor to give you this. Of course, your liver has to be good."

10 / 10
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23 Report
  • Anonymous
  • October 16, 2010

Diflucan (fluconazole) "Diflucan (50 mg) is effective, fast, and I had no side effects."

10 / 10
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56 Report
  • Mos...
  • May 3, 2008

"This takes 6+ months, but did clear up a decades-long infection."

9 / 10
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61 Report
  • Dan...
  • June 6, 2017

"Fluconazole cured my toenail fungus in 6 months. I am very grateful!"

10 / 10
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29 Report
  • Oll...
  • Taken for 6 months to 1 year
  • August 7, 2020

"Have taken 2 fluconazole pills weekly for a year and nail is worse than before. Time to visit a podiatrist"

1 / 10
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6 Report
  • sar...
  • June 28, 2021

"My nail infection is worse. Th doctor did test before give me medication also . I take these for one week a month for three months ."

1 / 10
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0 Report
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.