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Fungizone

Generic Name: amphotericin B (am foe TER i sin)
Brand Name: Fungizone

What is Fungizone?

Fungizone is an antifungal medication that fights infections caused by fungus.

Fungizone is used to treat serious, life-threatening fungal infections. It is not for use in treating a minor fungal infection such as a yeast infection of the mouth, esophagus, or vagina.

Fungizone may also be used for purposes not listed in this medication guide.

Important Information

This medicine is for serious, life-threatening fungal infections. It is not for use in treating a minor fungal infection (yeast infection) of the mouth, esophagus, or vagina.

Do not use Fungizone in larger amounts than recommended. An overdose can cause death.

Before taking this medicine

You should not receive this medicine if you are allergic to any formulation of Fungizone (Abelcet, AmBisome, Amphocin, Amphotec, or Fungizone).

To make sure Fungizone is safe for you, tell your doctor if you have:

  • heart disease;

  • diabetes;

  • kidney disease;

  • an electrolyte imbalance (such as low levels of potassium or magnesium in your blood);

  • if you are receiving blood transfusions; or

  • if you are receiving radiation treatments.

Fungizone is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether Fungizone passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

How is amphotericin B given?

Fungizone is injected into a vein through an IV. A healthcare provider will give you this injection.

The medicine must be given slowly through an IV infusion, and can take from 2 to 6 hours to complete.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Fungizone is injected.

Fungizone may need to be given for up to several weeks or months, depending on the infection being treated.

While receiving Fungizone, you may need frequent blood tests.

Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antifungal medicine. Fungizone will not treat a viral infection such as the common cold or flu.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your Fungizone injection.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Fungizone can be fatal.

What should I avoid while receiving Fungizone?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Fungizone side effects

Get emergency medical help if you have signs of an allergic reaction: hives; wheezing, difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • pale skin, easy bruising;

  • blood in your stools;

  • a light-headed feeling, like you might pass out;

  • seizure (convulsions);

  • jaundice (yellowing of the skin or eyes);

  • build-up of fluid in your lungs--anxiety, sweating, gasping for breath, cough with foamy mucus, chest pain, fast or uneven heart rate;

  • signs of a kidney problem--little or no urination; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath;

  • low potassium--confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling; or

  • signs of new infection--fever, chills, flu symptoms, mouth and throat ulcers, rapid and shallow breathing.

Common side effects may include:

See also: Side effects (in more detail)

What other drugs will affect Fungizone?

Other drugs may interact with amphotericin B, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

  • Your pharmacist can provide more information about Fungizone.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 2.03.

Date modified: February 01, 2018
Last reviewed: March 10, 2016

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