Fluconazole Alternatives Compared
| Fluconazole | Diflucan | Clotrimazole topical |
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| Fluconazole | Diflucan fluconazole | Clotrimazole topical |
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Fluconazole is an effective antifungal agent that can be given as a single dose for vaginal candidiasis. Prescribed for Candida Urinary Tract Infection, Candidemia, Blastomycosis, Bone Marrow... View more |
Prescribed for Candida Urinary Tract Infection, Candidemia, Blastomycosis, Bone Marrow Transplantation, Chronic Mucocutaneous Candidiasis, Coccidioidomycosis, Coccidioidomycosis - Meningitis... View more |
Prescribed for Cutaneous Candidiasis, Intertrigo, Tinea Corporis, Tinea Pedis, Vaginal Yeast Infection, Paronychia, Tinea Cruris, Tinea Versicolor. May also be prescribed off label for Balanoposthitis. View more |
Choose a suggestion below Vaginal Yeast Infection
Tinea Versicolor
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| More about Fluconazole | More about Diflucan (fluconazole) | More about Clotrimazole topical | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
| Availability | ||||||||||||||||||||||||||
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Prescription only |
Prescription only |
Prescription and OTC |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Fluconazole has an average rating of 6.4 out of 10 from a total of 496 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 29% reported a negative effect. |
Diflucan has an average rating of 6.0 out of 10 from a total of 138 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 35% reported a negative effect. |
Clotrimazole topical has an average rating of 8.7 out of 10 from a total of 25 ratings on Drugs.com. 86% of reviewers reported a positive effect, while 10% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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See the full fluconazole side effects document. |
See the full Diflucan side effects document. |
See the full clotrimazole topical side effects document. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all fluconazole prices |
View all Diflucan prices and generic prices |
View all clotrimazole topical prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Diflucan |
N/A |
Canesten, Canesten 1, Canesten 3, Canesten 6 Day Pessary, Clotrimazole-3, Clotrimazole-7, Desenex Antifungal Cream, Femcare, FungiCURE Pump Spray, Gyne-Lotrimin, Gyne-Lotrimin 3 Day, Lotrimin AF Athlete's Foot Cream, Lotrimin AF Jock Itch Cream, Lotrimin AF Ringworm Cream, Trivagizole 3 View more | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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50 hours |
50 hours |
N/A |
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| CSA Schedule** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
Single 150 Mg Tablet Use For Vaginal Candidiasis
Category D
Positive evidence of risk
All Indications (excluding Single 150 Mg Tablet Use For Vaginal Candidiasis) See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
Single 150 Mg Tablet Use For Vaginal Candidiasis
Category D
Positive evidence of risk
All Indications (excluding Single 150 Mg Tablet Use For Vaginal Candidiasis) See the full Pregnancy Warnings document. |
Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 535 drugs are known to interact with fluconazole:
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A total of 536 drugs are known to interact with Diflucan:
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No known drug interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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January 29, 1990 |
January 29, 1990 |
February 03, 1975 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.