Diflucan and Headaches: What Users Say

• Lil...
• Taken for 1 to 6 months
• January 20, 2017

For Vaginal Yeast Infection "I got one Diflucan pill to take, which I thought at first was a waste of money, but it works GREAT. The discharge and smell changed after 1 day! There were no side effects, no headaches, nausea, pain, etc. Highly recommend!"

• Sav...
• Taken for less than 1 month
• August 6, 2015

For Candida Urinary Tract Infection "Amazing drug. After trying everything for a week to get rid of the worst yeast infection of my life, I was prescribed Diflucan. Within 15 minutes, no lie, yeast started dumping from my body. Kinda gross, but that's what was making me feel so horrible and frustrated. I had waited a few days after Monistat didn't work. But word to the wise, drink lots of water after you take this; there are so many toxins that get released into your body when yeast dies off, especially that fast. I drank a lot of water and didn't experience side effects or headaches with this med."

• Ano...
• June 14, 2015

For Vaginal Yeast Infection "Took antibiotics and got a yeast infection, went to the Drs, they prescribed Monistat 3. Took it for the 3 days, still was experiencing a lot of itching and burning. Went back to the Drs, she prescribed the one-dose pill. Took it Thursday afternoon, felt nausea, had headaches, and stomach aches (side effects), but helped with the burning pain by the next day. It's now Sunday, and the itching, burning, and pain are back. Going back to the Drs tomorrow for the 3rd time in 2 and a half weeks. So want this to go away. Feeling like I need to get a second opinion."

• She...
• January 2, 2016

For Vaginal Yeast Infection "I took this pill 2 days ago. I have been sick ever since. I have an awful headache, constantly feel like throwing up, and I'm itchy. Stick to the cream, I have never had a reaction to any medications, so thought this would be fine. Don't risk it!"

• dem...
• Taken for less than 1 month
• January 20, 2022

For Vaginal Yeast Infection "I had a UTI, which I’m prone to. I tend to hold my pee when I am sleeping. I know, I know, it’s a bad habit, lol. Anyways, I have Keflex for UTI, and that caused a yeast infection. I thought I’d try some Monistat 7, and it only got worse. Finally, like three days into the Monistat, I was like I have to take the Diflucan. I was putting it off because apparently it interacts with Zoloft, but I called the pharmacist, and she was like nope, you’re fine, take the pill. I would say about an hour after the pill, I felt relief. I was so freaking swollen, irritated, and just in pain down there. I literally wanted to cry before taking the pill. I'm so happy to finally feel relief. For me, I had an upset stomach for like 30 mins, then it went away. A day or two later, I had a bad headache, but took some ibuprofen. Also, the dosage was 150 mg. Took it in the afternoon, like around 3 pm. Felt relief around 5 pm. Easy to use, not messy like the cream, actually will work…"

• kri...
• Taken for less than 1 month
• November 16, 2021

For Vaginal Yeast Infection "Glad to hear my 150 mg one-time dose can cause fatigue, tachycardia, and headache, as well as indigestion and heartburn. A lot of vague symptoms like shaking hands, burping, cold extremities too. I thought I had COVID again! I did drink alcohol on day 6 after taking it, which worsened my side effects severely. Now I know I only need to wait and drink a lot of ginger tea and water and keep my meals simple. This site helped me a lot. Don't drink alcohol with this, you'll regret it. No yeast infection, but now I feel sick three days after alcohol. It started with throbbing in my liver, then evolved 24 hours later into many minor, annoying symptoms."

• Hor...
• Taken for 1 to 6 months
• October 15, 2015

For Tinea Versicolor "After nine years with a fungal infection on the skin, I was given 100 MG/week for a month. I already took the last pill of the course, and all it has done so far is turn the spots pink and make them slightly bigger, and some itched more often (although one looks like it's starting to disappear)! But the side effects! Oh, the side effects! After the first pill, I felt extremely dizzy, headachy, and nauseous for an hour after bedtime. The next day, I had little appetite that only recovered that evening. The next two times, I took two Rolaids, which helped with the nausea. That left the headache to contend with all day the day after I took the pill. I took two ibuprofen three times to combat the headaches on the last pill. What a joke!"

• Ano...
• Taken for less than 1 month
• April 5, 2025

For Vaginal Yeast Infection "Treated for candida infection, 3 strains, and had lowered immunity. So had Canesten and Diflucan prescribed, 150 mg, fine for 1st day. Next day, severe migraine-like headaches that have lasted every day on and off, bar last 2 days. Off balance, anxiety, and severe nausea for 2 and a half, nearly 3 weeks now. Thrush has cleared up, but couldn't get my GP's surgery to give me an appointment for a couple of weeks. I've had this tablet before, no issues. Never again, feel really ill on it. I'm 65 and normally very active, have had to suspend my gym membership for a month as I feel so unwell. Do not take this drug."

• car...
• February 18, 2011

For Vaginal Yeast Infection "It cleared up my problem in just a few days, the only side effect I got was a headache, but other than that, I felt great! So happy my doctor gave it to me."

• Anonymous
• Taken for less than 1 month
• January 15, 2015

For Candida Urinary Tract Infection "I am still having problems with a bad taste in my mouth, no appetite, nausea after taking a single dose over a week ago. I suffered a very bad headache for 3 days after the dose. It was miserable."

• kun...
• Taken for less than 1 month
• February 23, 2021

For Vaginal Yeast Infection "Never again. One day after taking Diflucan, I got a splitting headache, severe dizziness, and nausea with vomiting."