Diflucan and Diarrhea: What Users Say

• Nic...
• Taken for less than 1 month
• January 10, 2021

For Vaginal Yeast Infection "I took Diflucan years ago for a yeast infection—got rid of it quickly and efficiently with no side effects! Fast forward to this year. I had a major yeast infection, took Diflucan but this time had multiple weird side effects, including: peeling/swollen lips (with ulcers on the inside), nausea/vomiting, terrible stomach pains and diarrhea, heart palpitations, itchy throat, and increased vaginal and anal irritation. I even developed hemorrhoids for the first time in my life, and I attribute it all to this drug. I think it severely irritated my mucous membranes and then this was only worsened by coupled chronic diarrhea I was having. Be really careful taking this drug... it’s no joke."

• beg...
• Taken for less than 1 month
• January 19, 2019

For Vaginal Yeast Infection "I asked my doctor for a prescription of Diflucan after Monistat 7 burned my insides worse than the infection itself! Diflucan has been great for me so far!! I was prescribed two 150 mg tablets—one to take ASAP, and the other to take three days later. I’m on day 2 of the pill being in my system, and let me tell you, although it takes a while for the pill to kick in, it really does work!!! Now, this didn’t work a mere couple of hours later for me, I didn’t start to feel relief until this morning, but a little over 24 hours after ingesting the pill, and the burning has completely gone away :) The itchiness is still prevalent, although it has subsided GREATLY. I’m still a bit sore, but that’s to be expected with a really bad yeast infection. The only side effects that I’ve really noticed with this pill are that it did leave a small patch of dry skin near my mouth (but as an eczema sufferer, this is nothing crazy for me to handle lol), and it really will give you the poops."

• Smi...
• May 5, 2011

For Vaginal Yeast Infection "I've taken this as needed over the years without any problem. This time, I had nausea, diarrhea, and dizziness. Our pharmacy gives a printout of all the possible side effects, and it says you can be allergic to it (as most drugs). I guess it just depends on the person on how much you need and how your body will react. It takes more than one dose for me."

• Anonymous
• August 5, 2010

For Vaginal Yeast Infection "I took Diflucan at the same time I was taking Metformin for high blood sugar. I had terrible side effects. Among them, redness and burning in my face, terrible joint pains, especially in my knees, vomiting, diarrhea, and upset stomach."

• whi...
• Taken for 10 years or more
• April 24, 2018

For Cryptococcal Meningitis, Immunosuppressed Host "I was diagnosed with cryptococcal meningitis. Was treated with fluconazole when it was a new drug instead of the accepted amphotericin B. With the newer fluconazole, the infection was controlled without the need for inpatient hospitalization. Fluconazole has a few side effects, like diarrhea, but it ended up being mild. My biggest problem with the pill was that it would easily break down in the mouth and throat. If not taken with plain water and swallowed very quickly, it would dissolve and stick in the throat, causing gagging and leaving a foul taste for hours. On the other hand, the drug was very effective for a life-threatening condition. The few downsides were outweighed by the overwhelming benefits. The old treatment is much harsher than the fluconazole. My vote goes hand down in favor of fluconazole. Barring complications, a lifelong maintenance dose will be required, but again, a small inconvenience."

• Dia...
• Taken for 2 to 5 years
• August 6, 2025

For Chronic Mucocutaneous Candidiasis "I take this medication 3 x a week for maintenance purposes per my doctor; I took one this AM and by 3 pm I had diarrhea. I think I know where my diarrhea problems are coming from now."