Diflucan and Blisters: What Users Say

• Sev...
• Taken for less than 1 month
• January 25, 2017

For Vaginal Yeast Infection "I have taken this medication before, so not sure if something with my body chemistry changed or this medication composition has changed. My experience was a severe allergic reaction causing swelling to my face and lips, with blistering and sores inside my mouth that were extremely painful. I was given a steroid shot and high dosages of prednisone. On day 5, the swelling has just started to go down, but the sores inside my mouth and the scabs on my lips are horrible. I will not take this medication again."

• Kik...
• Taken for 2 to 5 years
• September 7, 2019

For Vaginal Yeast Infection "Have taken sporadically for a yeast infection. Seemed to work, but I broke out in hives. It took me a bit to figure it out because I’d take 1 pill maybe once a year. It didn’t register. Well, now I know! I took 1 pill in March, 1 pill in July, and thought, huh, I wonder if fluconazole. Took 1 pill yesterday and paid attention!!! Yep! Ugh! Hives and allergic reaction not on the list! I get hives, my knuckle swells on 1 finger, and it is painful. It blisters and finally pops and heals on its own. Each time it is worse. Now my lips are swollen, and hives on palms and on skin by thumb. My hands are so dry. NEVER AGAIN WILL I TAKE THIS fluconazole!!"

• Bad...
• Taken for less than 1 month
• January 19, 2019

For Vaginal Yeast Infection "I have taken Diflucan for yeast infections for years. I always get the infection after having to take antibiotics for a sinus infection (at least 1x/year). I have never had any issues - until now. Twelve hours after taking the Diflucan, I developed 3 hives - two on my face and one on my thumb. I thought maybe it was from something else or stress, so I ignored it. Big mistake. Had to take a second pill this week, and the hives came back in the exact same places, only worse, and have blistered. I also now have blisters inside my mouth and on my lips. They are extremely painful and are healing, but still there after 6 days. I expect scarring. If you have an allergic reaction to this drug, DO NOT take it again. It only gets worse. Now to figure out what I CAN take, as the yeast infection is still there."

• FDE...
• May 14, 2019

For Vaginal Yeast Infection "I took Diflucan last year, and my vaginal yeast infection cleared up in a day, no allergic reactions. I recently needed to take it again earlier this year, and my upper lip became swollen with a tiny sore/blister on the underside of my lip. The right side of my face was also slightly swollen and numb. The pharmacist didn’t think it was related to Diflucan because I hadn’t had a reaction before. Well, was she wrong! I had to take it again a couple of days ago, and the exact allergic reaction returned (which I realize is most likely a Fixed Drug Eruption). This time, my upper lip is much worse, with a sore in the same spot, and it’s taking longer to disappear. Both times I’ve been taking antihistamines to help. If you experience an allergic reaction after taking Diflucan, think very carefully about taking it again."

• Cry...
• Taken for less than 1 month
• July 30, 2019

For Vaginal Yeast Infection "Was prescribed this medication after BV treatment, and the next day, lip was swollen & itching. Lip swelled to the point it was tight and shiny. Eating was unbearable. Woke up with a blister that has since popped, and now I have an open sore and scabs. I WILL NOT EVER TAKE THIS MEDICATION AGAIN!"

• Ang...
• July 21, 2017

For Vaginal Yeast Infection "After taking Diflucan, I experienced blisters on both pinky fingers and toes, as well as the palms and bottoms of my feet. It was painful and uncomfortable, the side effects passed after a couple of days. However, the yeast cleared up instantly. I will NEVER use the product again."

• Lin...
• Taken for less than 1 month
• August 9, 2022

For Vaginal Yeast Infection "I am always prescribed this drug when I get a yeast infection. The past 3 times I have taken it, it causes a couple of my fingers to swell and itch. By the next day, I always have a blister on my finger! I have developed an allergy to this medication. I will never take it again!!!"