Efinaconazole Topical Dosage

Medically reviewed by Drugs.com. Last updated on May 19, 2025.

Usual Adult Dose for Onychomycosis - Toenail

Apply to affected toenail(s) once a day for 48 weeks.

Comments:

• The integrated flow-through brush applicator should be used.
• The toenail, toenail folds, toenail bed, hyponychium, and undersurface of the toenail plate should be completely covered.

Use: For the topical treatment of onychomycosis of the toenail(s) due to Trichophyton rubrum and T mentagrophytes

Usual Pediatric Dose for Onychomycosis - Toenail

6 years or older: Apply to affected toenail(s) once a day for 48 weeks.

Comments:

• The integrated flow-through brush applicator should be used.
• The toenail, toenail folds, toenail bed, hyponychium, and undersurface of the toenail plate should be completely covered.

Use: For the topical treatment of onychomycosis of the toenail(s) due to T rubrum and T mentagrophytes

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS: None

Safety and efficacy have not been established in patients younger than 6 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• For topical use only; not for oral, ophthalmic, or intravaginal use
• Apply to clean, dry toenails; wait at least 10 minutes after showering, bathing, or washing before applying.

Storage requirements:

• Store at 20C to 25C (68F to 77F); excursions permitted to 15C to 30C (59F to 86F).
• Keep away from heat or flame; do not freeze.
• Keep bottle closed tightly; store upright.

Patient advice:

• Read the US FDA-approved patient labeling (Patient Information and Instructions for Use).
• Do not use near heat or open flame; product is flammable.
• Use on affected toenails and immediately adjacent skin only.
• Consult healthcare professional if application area shows signs of persistent irritation (e.g., redness, itching, swelling).
• The impact of nail polish or other cosmetic nail products on the efficacy of this drug has not been established.

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer