Zonegran Alternatives Compared
| Zonegran | Keppra | Levetiracetam |
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| Zonegran zonisamide | Keppra levetiracetam | Levetiracetam |
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Prescribed for Seizures. May also be prescribed off label for Migraine Prevention, Benign Essential Tremor, Parkinsonian Tremor. |
Keppra is an anticonvulsant that is used in conjunction with other medications for the treatment of certain types of seizures. It may cause drowsiness but it is less likely than some other... View more |
Levetiracetam is an anticonvulsant that is used in conjunction with other medications for the treatment of certain types of seizure. It may cause drowsiness but interactions with other medications... View more |
Choose a suggestion below Seizures (Convulsions)
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| More about Zonegran (zonisamide) | More about Keppra (levetiracetam) | More about Levetiracetam | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
| Availability | ||||||||||||||||||||||||||
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Prescription only |
Prescription only |
Prescription only |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Zonegran has an average rating of 6.6 out of 10 from a total of 63 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 23% reported a negative effect. |
Keppra has an average rating of 5.7 out of 10 from a total of 262 ratings on Drugs.com. 43% of reviewers reported a positive effect, while 33% reported a negative effect. |
Levetiracetam has an average rating of 5.9 out of 10 from a total of 376 ratings on Drugs.com. 45% of reviewers reported a positive effect, while 32% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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See the full Zonegran side effects document. |
Common side effects include: infection, neurosis, drowsiness, asthenia, headache, nasopharyngitis, nervousness, abnormal behavior, aggressive behavior, agitation, anxiety, apathy, depersonalization, depression, fatigue, hostility, hyperkinetic muscle activity, personality disorder, emotional lability, irritability, laceration, mood changes. See the full Keppra side effects document. |
Commonly reported side effects include: infection, neurosis, drowsiness, asthenia, headache, nasopharyngitis, nervousness, abnormal behavior, aggressive behavior, agitation, anxiety, apathy, depersonalization, depression, fatigue, hostility, hyperkinetic muscle activity, mental disorders, outbursts of anger, personality disorder, emotional lability, irritability, laceration, mood changes. See the full levetiracetam side effects document. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Zonegran prices and generic prices |
View all Keppra prices and generic prices |
View all levetiracetam prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
Other levetiracetam brands include: Elepsia XR, Keppra XR, Roweepra, Roweepra XR, Spritam | Elepsia XR, Keppra, Keppra XR, Roweepra, Roweepra XR, Spritam | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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63 hours |
8 hours |
8 hours |
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| CSA Schedule** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 378 drugs are known to interact with Zonegran:
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A total of 228 drugs are known to interact with Keppra:
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A total of 228 drugs are known to interact with levetiracetam:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| First Approval Date | ||||||||||||||||||||||||||
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March 27, 2000 |
November 30, 1999 |
November 30, 1999 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.