Comparing Spironolactone vs Yaz
| Spironolactone | Yaz |
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| Spironolactone | Yaz (drospirenone / ethinyl estradiol) |
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Prescription only
Spironolactone is a diuretic that may be used to remove excess fluid (edema) from the body, lower blood pressure, or treat hyperaldosteronism. It does not cause potassium loss from the body; however... View more |
Prescription only
Prescribed for Premenstrual Dysphoric Disorder, Acne, Birth Control. Yaz may also be used for purposes not listed in this medication guide. |
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| More about Spironolactone | More about Yaz (drospirenone / ethinyl estradiol) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Spironolactone has an average rating of 6.9 out of 10 from a total of 695 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 24% reported a negative effect. |
Yaz has an average rating of 5.9 out of 10 from a total of 989 ratings on Drugs.com. 45% of reviewers reported a positive effect, while 32% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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See also: spironolactone side effects in more detail. |
See also: Yaz side effects in more detail. |
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| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all spironolactone prices |
View all Yaz prices |
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| Dosage Forms Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Aldactone, CaroSpir | Other drospirenone / ethinyl estradiol brands include: Gianvi, Jasmiel, Lo-Zumandimine, Loryna, Melamisa, Nikki, Ocella, Syeda, Yaela, Yasmin, Zarah, Zumandimine View more | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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37 hours |
32.5 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 383 drugs are known to interact with spironolactone:
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A total of 558 drugs are known to interact with Yaz:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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January 21, 1960 |
March 16, 2006 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.