Comparing Prochlorperazine vs Promethazine
| Prochlorperazine | Promethazine |
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| Prochlorperazine | Promethazine |
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Prescription and OTC
Prochlorperazine is used to treat severe nausea or vomiting or to improve mood in conditions such as schizophrenia or anxiety. It is associated with a wide range of side effects, including drowsiness... View more |
Prescription only
Promethazine is used to treat and prevent allergies (rhinitis, conjunctivitis, skin reactions), for anaphylaxis support, for motion sickness/nausea, as a sedative, and for dermatological conditions... View more |
Related suggestions Nausea/Vomiting
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| More about Prochlorperazine | More about Promethazine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Prochlorperazine has an average rating of 3.1 out of 10 from a total of 461 ratings on Drugs.com. 19% of reviewers reported a positive effect, while 74% reported a negative effect. |
Promethazine has an average rating of 7.2 out of 10 from a total of 398 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 21% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Prochlorperazine side effects |
View all Promethazine side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Prochlorperazine prices |
View all Promethazine prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Compro | Adgan, Anergan 50, Antinaus 50, Phenadoz, Promethegan | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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23 hours |
16 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 690 drugs are known to interact with Prochlorperazine:
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A total of 692 drugs are known to interact with Promethazine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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October 23, 1956 |
March 29, 1951 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.