Comparing Phenelzine vs Tranylcypromine

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Phenelzine	Tranylcypromine	Enter another drug to compare

Phenelzine

Tranylcypromine

Prescription only

Prescribed for Depression, Migraine Prevention. Phenelzine may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for Depression. Tranylcypromine may also be used for purposes not listed in this medication guide.

More about Phenelzine

More about Tranylcypromine

Ratings & Reviews

Phenelzine has an average rating of 8.2 out of 10 from a total of 157 ratings on Drugs.com. 75% of reviewers reported a positive effect, while 10% reported a negative effect.

Tranylcypromine has an average rating of 8.4 out of 10 from a total of 127 ratings on Drugs.com. 83% of reviewers reported a positive effect, while 9% reported a negative effect.

View all 157 reviews

View all 127 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Weight gain (12.1%)
Anxiety (6.4%)
Depression (5.7%)
Insomnia (5.1%)
Nausea (4.5%)
Tiredness (3.8%)
Blood pressure (3.2%)

View all Phenelzine side effects

Insomnia (12.6%)
Blood pressure (7.1%)
Anxiety (4.7%)
Fatigue (3.9%)
High blood pressure (3.9%)
Drowsiness (3.1%)
Irritability (3.1%)

View all Tranylcypromine side effects

Drug Class

Monoamine oxidase inhibitors

Monoamine oxidase inhibitors

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	60 tablet
Strength	15 mg
Per unit^*	$0.42
Cost^*	$25.03

View all Phenelzine prices

Quantity	100 tablet
Strength	10 mg
Per unit^*	$0.82 - $1.18
Cost^*	$82.47 - $118.27

View all Tranylcypromine prices

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Dosage Forms

Oral tablet

Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

84 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Category N Not classified

See the full pregnancy warnings document.

Drug Interactions

A total of 544 drugs are known to interact with Phenelzine:

153 major drug interactions (721 brand and generic names)
385 moderate drug interactions (1671 brand and generic names)
6 minor drug interactions (16 brand and generic names)

A total of 543 drugs are known to interact with Tranylcypromine:

153 major drug interactions (721 brand and generic names)
383 moderate drug interactions (1665 brand and generic names)
7 minor drug interactions (17 brand and generic names)

Alcohol/Food/Lifestyle Interactions

During and within two weeks after treatment with phenelzine, you must not consume any foods or... View more

During and within two weeks after treatment with tranylcypromine, you must not consume any foods or... View more

Disease Interactions

First Approval Date

June 09, 1961

February 21, 1961

WADA Class View classifications

N/A

More Information

Patient Resources

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Phenelzine vs Tranylcypromine

See also:

Lexapro

Abilify

Rexulti

Zoloft

Seroquel

Prozac

Cymbalta

Wellbutrin

Zyprexa

Celexa

Further information

Comparing Phenelzine vs Tranylcypromine

See also:

Further information

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