Perphenazine Alternatives Compared
| Perphenazine | Vraylar (cariprazine) | Caplyta (lumateperone) |
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| Perphenazine | Vraylar (cariprazine) | Caplyta (lumateperone) |
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Prescription only
Prescribed for Psychosis, Bipolar Disorder, Nausea/Vomiting. Perphenazine may also be used for purposes not listed in this medication guide. |
Prescription only
Vraylar is an atypical antipsychotic that is effective for the treatment of schizophrenia and bipolar I disorder. Vraylar is usually well-tolerated and less likely than some other antipsychotics to... View more |
Prescription only
Caplyta is an atypical antipsychotic that is used to treat adults with schizophrenia or depression associated with bipolar disorder. Sleepiness is the most common side effect and it should not be... View more |
Related suggestions Bipolar Disorder
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| More about Perphenazine | More about Vraylar (cariprazine) | More about Caplyta (lumateperone) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Perphenazine has an average rating of 7.0 out of 10 from a total of 36 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 19% reported a negative effect. |
Vraylar has an average rating of 6.1 out of 10 from a total of 524 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 32% reported a negative effect. |
Caplyta has an average rating of 6.6 out of 10 from a total of 185 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 29% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
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View all Perphenazine side effects |
View all Vraylar side effects |
View all Caplyta side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Perphenazine prices |
View all Vraylar prices |
View all Caplyta prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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9 hours |
504 hours |
18 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 716 drugs are known to interact with Perphenazine:
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A total of 577 drugs are known to interact with Vraylar:
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A total of 605 drugs are known to interact with Caplyta:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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February 27, 1957 |
September 17, 2015 |
December 20, 2019 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.