Comparing Paxil vs Zoloft
| Paxil (paroxetine) | Zoloft (sertraline) |
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| Paxil (paroxetine) | Zoloft (sertraline) |
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Prescription only
Paxil may be used for the treatment of depression, anxiety, or post-traumatic stress disorder. It should be tapered off slowly on discontinuation. Prescribed for Anxiety and Stress, Dysautonomia... View more |
Prescription only
Zoloft is a brand name for sertraline which is an effective antidepressant with less potential for drowsiness than many other antidepressants. It belongs to the group of medicines called selective... View more |
Related suggestions Depression
Major Depressive Disorder
Panic Disorder
Obsessive Compulsive Disorder
Popular comparisons
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| More about Paxil (paroxetine) | More about Zoloft (sertraline) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Paxil has an average rating of 7.1 out of 10 from a total of 962 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 20% reported a negative effect. |
Zoloft has an average rating of 7.3 out of 10 from a total of 1976 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Paxil side effects |
View all Zoloft side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Paxil prices |
View all Zoloft prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other paroxetine brands include: Brisdelle, Paxil CR |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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21 hours |
66 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category D
Positive evidence of risk
Excluding Brisdelle
Category X
Not for use in pregnancy
Brisdelle See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 510 drugs are known to interact with Paxil:
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A total of 673 drugs are known to interact with Zoloft:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 29, 1992 |
December 30, 1991 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Auvelity
Auvelity (dextromethorphan and bupropion) is used to treat major depressive disorder. Includes ...
Prozac
Prozac (fluoxetine) is an SSRI antidepressant used to treat depression, OCD, panic disorder ...
Vraylar
Vraylar is a once a day antipsychotic medication used to treat mental health or mood disorders ...
Celexa
Celexa (citalopram) is an antidepressant in a group of drugs called selective serotonin reuptake ...
Luvox
Luvox is used for anxiety and stress, obsessive compulsive disorder
Paxil CR
Paxil CR is used for anxiety, depression, dysautonomia, generalized anxiety disorder, major ...
Luvox CR
Luvox CR is used for anxiety and stress, obsessive compulsive disorder, social anxiety disorder
Prozac Weekly
Prozac Weekly is used for anxiety and stress, bulimia, depression, major depressive disorder ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.