Comparing Olanzapine vs Seroquel
Olanzapine Remove Olanzapine from your drug comparison | Seroquel Remove Seroquel from your drug comparison |
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Olanzapine Remove Olanzapine from your drug comparison | Seroquel quetiapine Remove Seroquel from your drug comparison | ||||||||||||||||
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Olanzapine is an antipsychotic used in the treatment of schizophrenia and bipolar disorder. Weight gain associated with olanzapine is common. Prescribed for Agitated State, Bipolar Disorder,... View more |
Seroquel is an antipsychotic that helps to calm and relieve psychotic thoughts. It is often given because it is quite sedating; however, care is needed because it also lowers blood pressure.... View more |
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Prescription only |
Prescription only |
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Ratings & ReviewsRecent helpful reviews |
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6.0
For Bipolar Disorder: I was 150 pounds and I went up to 182 pounds within two months of using olanzapine. You are hungry all of the time on this medication and never feel satisfied. The first two weeks of medication use I felt very tired. I am still tired, but it's not as bad as it was. I started on 15 mg. I dropped down to 10 mg. The unpleasant side effects described continued. I am in the process of getting off this medication. |
7.0
For Bipolar Disorder: If you have Bipolar Disorder type II, please learn as much as you can about this condition from professional, reputable sources so you can make informed decisions about treatment and management options. This is a treatable, manageable illness, take hope in that. After 20+ years struggling to "cure" myself "naturally" & being miserable, dangerously depressed & dysfunctional, I finally decided to try psych medication. I found a doctor who SPECIALISES in this disorder and is up to date with the latest research findings in this specific condition. If you don't like your current GP or Psych's attitude, find someone else! I started a combo of Lamictal (AM & PM) & Seroquel (Only PM - makes you drowsy). I kept a daily mood diary & it took 3 months for my mood to fully stabilise. To help the bipolar depression, we added bupropion & N-Acetyl Cysteine, a supplement (all based on clinical research!). For 5 years now, I’ve had my life back. Deciding to take this medication saved my life. For Bipolar Disorder: I was hospitalized 17 years ago with a major manic mixed episode. It was worst thing on earth. Was given 200 milligrams of serequel and it calmed down the demons. Tapered the dose down in months time come and stayed successfully at 50 milligrams for following 17 years. Long term side effects began with bloods changed, elevated blood sugar and triglycerides. Weaned and got off it, took several weeks. Feeling better with more clarity and regular movements now. Those two weeks of getting out of my system caused side effects of weird dreams, body aches and mood swings. Hard time sleeping. Increases over the counter supplements and made sure my life was low key until things settled. I’m grateful for the med. If not for the side effects which would have led to diabetes I would have remained in it. But I believe in the beginning it saved my life. |
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Drug Class |
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Side Effects |
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Commonly reported side effects include: asthenia, dizziness, drowsiness, extrapyramidal reaction, hyperkinetic muscle activity, akinesia, cogwheel rigidity, drug-induced parkinson's disease, dyspepsia, mask-like face, and xerostomia. See the full olanzapine side effects document. |
Common side effects include: asthenia, constipation, dizziness, drowsiness, headache, increased serum cholesterol, increased serum triglycerides, increased thyroid stimulating hormone level, and xerostomia. See the full Seroquel side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all olanzapine prices |
View all Seroquel prices and generic prices |
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Generic Availability |
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Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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Zyprexa, Zyprexa Intramuscular, Zyprexa Relprevv, Zyprexa Zydis | Other quetiapine brands include: Seroquel XR | ||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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54 hours |
6 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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FDA Alerts |
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Drug Interactions |
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A total of 597 drugs are known to interact with olanzapine:
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A total of 649 drugs are known to interact with Seroquel:
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Alcohol/Food/Lifestyle Interactions |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions |
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First Approval Date |
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September 30, 1996 |
September 26, 1997 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
For Bipolar Disorder: Took 40mg per day for about a year before I really "came back to life." It helped me sleep but was too sedating overall. It helped me reverse anorexia but I doubled my weight (gained 93 lbs in a few months.) It did stop the psychosis. Was able to feel emotions again after years of numbness. Took varying doses for 17 yrs and had very hard time getting off it when the time was right. Have been off 5 months now and am considering starting again because of severe insomnia & mood swings. Hate the weight gain and lethargy.