Comparing Novolog vs Tirzepatide

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Novolog (insulin aspart)	Tirzepatide	Enter another drug to compare

Novolog (insulin aspart)

Tirzepatide

Prescription only

Prescribed for Type 2 Diabetes, Diabetes - Type 1, Diabetic Ketoacidosis, Nonketotic Hyperosmolar Syndrome. Novolog may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for Weight Loss (Obesity/Overweight), Obstructive Sleep Apnea/Hypopnea Syndrome, Type 2 Diabetes. Tirzepatide may also be used for purposes not listed in this medication guide.

More about Novolog (insulin aspart)

More about Tirzepatide

Ratings & Reviews

Novolog has an average rating of 5.5 out of 10 from a total of 32 ratings on Drugs.com. 31% of reviewers reported a positive effect, while 34% reported a negative effect.

Tirzepatide has an average rating of 8.6 out of 10 from a total of 1947 ratings on Drugs.com. 80% of reviewers reported a positive effect, while 5% reported a negative effect.

View all 32 reviews

View all 1947 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Novolog side effects

Nausea (18.2%)
Constipation (12.7%)
Diarrhea (8.1%)
Vomiting (4.6%)
Burping (4.5%)
Upset stomach (4.2%)
Loss of appetite (4.1%)

View all Tirzepatide side effects

Drug Class

Insulin

GLP-1 Agonists (Incretin Mimetics)

Generic Availability

N/A

Pricing and Coupons * Prices are without insurance

Quantity	10 mL
Strength	100 units/mL
Per unit^*	$8.72
Cost^*	$87.23

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Dosage Forms

Injectable solution
Subcutaneous solution

N/A

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

1.5 hours

120 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category B No proven risk in humans

See the full pregnancy warnings document.

Summary unavailable.

See the full pregnancy warnings document.

Drug Interactions

A total of 394 drugs are known to interact with Novolog:

15 major drug interactions (39 brand and generic names)
358 moderate drug interactions (1888 brand and generic names)
21 minor drug interactions (210 brand and generic names)

A total of 414 drugs are known to interact with Tirzepatide:

15 major drug interactions (34 brand and generic names)
398 moderate drug interactions (2272 brand and generic names)
1 minor drug interactions (10 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood... View more

Tirzepatide may affect the absorption of other medications that you take by mouth. In some cases... View more
Talk to your doctor before using alcohol together with tirzepatide. Alcohol may affect blood... View more

Disease Interactions

First Approval Date

June 07, 2000

N/A

WADA Class View classifications

N/A

More Information

Patient Resources

Novolog uses

Tirzepatide uses

Professional Resources

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Novolog vs Tirzepatide

See also:

Ozempic

Rybelsus

Mounjaro

Trulicity

Lantus

Tresiba

Victoza

Basaglar

Humalog

Levemir

Further information

Comparing Novolog vs Tirzepatide

See also:

Further information

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