Norethindrone Alternatives Compared
| Norethindrone | Mirena | Nexplanon |
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| Norethindrone | Mirena (levonorgestrel) | Nexplanon (etonogestrel) |
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Prescription only
Prescribed for Amenorrhea, Abnormal Uterine Bleeding, Endometriosis, Birth Control. May also be prescribed off label for Gender Affirming Hormone Therapy . |
Prescription only
Prescribed for Abnormal Uterine Bleeding, Birth Control. Mirena may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Birth Control. Nexplanon may also be used for purposes not listed in this medication guide. |
Related suggestions Birth Control (Contraception)
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| More about Norethindrone | More about Mirena (levonorgestrel) | More about Nexplanon (etonogestrel) | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
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No lower-cost generic available |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Norethindrone has an average rating of 4.8 out of 10 from a total of 1508 ratings on Drugs.com. 32% of reviewers reported a positive effect, while 46% reported a negative effect. |
Mirena has an average rating of 6.1 out of 10 from a total of 2559 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 32% reported a negative effect. |
Nexplanon has an average rating of 5.1 out of 10 from a total of 4800 ratings on Drugs.com. 32% of reviewers reported a positive effect, while 42% reported a negative effect. |
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| Side Effects | ||||||||||||||||||||||||||
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Commonly reported side effects include:
See also: norethindrone side effects in more detail. |
See also: Mirena side effects in more detail. |
Common side effects include:
See also: Nexplanon side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all norethindrone prices |
View all Mirena prices and generic prices |
View all Nexplanon prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Affodel, Camila, Deblitane, Emzahh, Errin, Heather, Incassia, Jencycla, Lyleq, Lyza, Nor-QD, Norlyda, Norlyroc, Sharobel, Tulana View more | Other levonorgestrel brands include: Aftera, AfterPill, AfterPlan, Athentia Next, BionaFem, EContra EZ, EContra One-Step, Fallback Solo, Kyleena, Liletta, Morning After, My Choice, My Way, New Day, Next Choice One Dose, Opcicon One-Step, Option 2, Plan B One-Step, PostDay One-Step, Preventeza, React, Skyla, Take Action View more |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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10 hours |
45 hours |
25 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 242 drugs are known to interact with norethindrone:
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A total of 236 drugs are known to interact with Mirena:
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A total of 223 drugs are known to interact with Nexplanon:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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July 30, 2012 |
N/A |
N/A |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient resources | ||||||||||||||||||||||||||
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N/A |
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| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.