Nikki Alternatives Compared
| Nikki (drospirenone / ethinyl estradiol) | Mirena (levonorgestrel) | Nexplanon (etonogestrel) |
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| Nikki (drospirenone / ethinyl estradiol) | Mirena (levonorgestrel) | Nexplanon (etonogestrel) |
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Prescription only
Prescribed for Premenstrual Dysphoric Disorder, Acne, Birth Control. Nikki may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Heavy Menstrual Bleeding, Birth Control. Mirena may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Birth Control. Nexplanon may also be used for purposes not listed in this medication guide. |
Related suggestions |
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| More about Nikki (drospirenone / ethinyl estradiol) | More about Mirena (levonorgestrel) | More about Nexplanon (etonogestrel) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Nikki has an average rating of 4.6 out of 10 from a total of 259 ratings on Drugs.com. 32% of reviewers reported a positive effect, while 49% reported a negative effect. |
Mirena has an average rating of 6.1 out of 10 from a total of 2624 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 32% reported a negative effect. |
Nexplanon has an average rating of 5.0 out of 10 from a total of 4865 ratings on Drugs.com. 32% of reviewers reported a positive effect, while 43% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Nikki side effects |
View all Mirena side effects |
View all Nexplanon side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
| Lower cost generic approved | ||||||||||||||||||||||||||
| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Nikki prices |
View all Mirena prices |
View all Nexplanon prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Other drospirenone / ethinyl estradiol brands include: Gianvi, Jasmiel, Lo-Zumandimine, Loryna, Melamisa, Ocella, Syeda, Yaela, Yasmin, Yaz, Zarah, Zumandimine View more | Other levonorgestrel brands include: Aftera, AfterPill, AfterPlan, Athentia Next, Curae, EContra One-Step, Fallback Solo, Her Style, Julie, Kyleena, Liletta, Morning After, My Choice, My Way, New Day, Next Choice One Dose, Opcicon One-Step, Option 2, Optionelle, Plan B One-Step, PostDay One-Step, SheWise, Skyla, Take Action View more |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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32.5 hours |
45 hours |
25 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 590 drugs are known to interact with Nikki:
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A total of 261 drugs are known to interact with Mirena:
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A total of 250 drugs are known to interact with Nexplanon:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||||||||||
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| First Approval Date | ||||||||||||||||||||||||||
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May 27, 2014 |
N/A |
July 17, 2006 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient Resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.