Nikki Interactions
There are 547 drugs known to interact with Nikki (drospirenone/ethinyl estradiol), along with 19 disease interactions, and 5 alcohol/food interactions. Of the total drug interactions, 70 are major, 435 are moderate, and 42 are minor.
- View all 547 medications that may interact with Nikki
- View Nikki alcohol/food interactions (5)
- View Nikki disease interactions (19)
Most frequently checked interactions
View interaction reports for Nikki (drospirenone / ethinyl estradiol) and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- Adderall XR (amphetamine / dextroamphetamine)
- albuterol
- Allegra (fexofenadine)
- Benadryl (diphenhydramine)
- bupropion
- buspirone
- clonazepam
- doxycycline
- fluoxetine
- fluticasone nasal
- gabapentin
- hydroxyzine
- ibuprofen
- lamotrigine
- lorazepam
- melatonin
- omeprazole
- ondansetron
- prednisone
- propranolol
- Prozac (fluoxetine)
- sertraline
- spironolactone
- trazodone
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Wellbutrin XL (bupropion)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Nikki alcohol/food interactions
There are 5 alcohol/food interactions with Nikki (drospirenone / ethinyl estradiol).
Nikki disease interactions
There are 19 disease interactions with Nikki (drospirenone / ethinyl estradiol) which include:
- smoking
- hyperkalemia
- abnormal vaginal bleeding
- carcinomas (estrogenic)
- hypercalcemia in breast cancer
- hypertension
- thromboembolism/cardiovascular
- hepatic neoplasms
- angioedema
- gallbladder disease
- hypercalcemia
- hyperlipidemia
- liver disease
- melasma
- depression
- fluid retention
- glucose intolerance
- retinal thrombosis
- thyroid function tests
More about Nikki (drospirenone / ethinyl estradiol)
- Nikki consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (256)
- Drug images
- Latest FDA alerts (5)
- Side effects
- Dosage information
- During pregnancy
- Drug class: contraceptives
- En español
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.