Nexlizet Alternatives Compared
| Nexlizet (bempedoic acid/ezetimibe) | Repatha (evolocumab) | Leqvio (inclisiran) |
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| Nexlizet (bempedoic acid/ezetimibe) | Repatha (evolocumab) | Leqvio (inclisiran) |
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Prescription only
Nexlizet contains ezetimibe and bempedoic acid and has been shown to decrease LDL-C levels by more than either drug alone. It is usually given in combination with other cholesterol-lowering... View more |
Prescription only
Repatha is a PCSK9 inhibitor that may be used to reduce LDL-C levels in people with primary hyperlipidemia and HoFH, and also to reduce the risk of cardiovascular events in adults with established... View more |
Prescription only
Prescribed for High Cholesterol - Familial Heterozygous, High Cholesterol. Leqvio may also be used for purposes not listed in this medication guide. |
Related suggestions High Cholesterol
High Cholesterol, Familial Heterozygous
Popular comparisons
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| More about Nexlizet (bempedoic acid/ezetimibe) | More about Repatha (evolocumab) | More about Leqvio (inclisiran) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Nexlizet has an average rating of 9.2 out of 10 from a total of 13 ratings on Drugs.com. 85% of reviewers reported a positive effect, while 0% reported a negative effect. |
Repatha has an average rating of 5.4 out of 10 from a total of 675 ratings on Drugs.com. 42% of reviewers reported a positive effect, while 44% reported a negative effect. |
Leqvio has an average rating of 7.2 out of 10 from a total of 77 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 5% reported a negative effect. |
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| Side Effects | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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N/A |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Nexlizet prices |
View all Repatha prices |
View all Leqvio prices |
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| Dosage Forms Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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22 hours |
408 hours |
9 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 110 drugs are known to interact with Nexlizet:
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A total of 2 drugs are known to interact with Repatha:
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No known drug interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | ||||||||||||||||||||||||||
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February 26, 2020 |
August 27, 2015 |
N/A |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.