Comparing Methadone vs Subutex
| Methadone | Subutex (buprenorphine) |
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| Methadone | Subutex (buprenorphine) |
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Prescription only
Methadone is a potent opioid analgesic that may be used to relieve severe pain unresponsive to other strong pain relievers; however, it is more commonly used to treat opioid addiction. There is a... View more |
Prescription only
Subutex was a brand name of sublingual buprenorphine, but it has been discontinued. [Suboxone](https://www.drugs.com/suboxone.html), which contains buprenorphine and naloxone, may be used instead... View more |
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| More about Methadone | More about Subutex (buprenorphine) | ||||||||
| Ratings & Reviews | |||||||||
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Methadone has an average rating of 8.7 out of 10 from a total of 607 ratings on Drugs.com. 84% of reviewers reported a positive effect, while 6% reported a negative effect. |
Subutex has an average rating of 8.5 out of 10 from a total of 145 ratings on Drugs.com. 81% of reviewers reported a positive effect, while 6% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Methadone side effects |
View all Subutex side effects |
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| Drug Class | |||||||||
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None |
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| Generic Availability | |||||||||
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Lower cost generic |
Lower cost generic approved | ||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||
View all Methadone prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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N/A |
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| Brand Names | |||||||||
| Methadone Diskets, Methadose, Methadose Sugar-Free | Other buprenorphine brands include: Belbuca, Brixadi, Buprenex, Butrans, Sublocade | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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30 hours |
48 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 845 drugs are known to interact with Methadone:
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A total of 726 drugs are known to interact with Subutex:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
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| First Approval Date | |||||||||
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August 13, 1947 |
October 08, 2002 |
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| WADA Class View classifications | |||||||||
| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
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N/A |
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| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.