Comparing Metformin vs Semaglutide
| Metformin | Semaglutide |
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| Metformin | Semaglutide |
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Prescription only
Metformin improves how the body responds to insulin and it is used to treat type 2 diabetes. Taste disturbances, diarrhea, and other stomach-related side effects are common side effects. Metformin is... View more |
Prescription only
Semaglutide (Ozempic, Rybelsus) lowers blood sugar levels by mimicking the effects of GLP-1, a naturally occurring hormone that stimulates insulin secretion and lowers glucagon secretion from the... View more |
Related suggestions |
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| More about Metformin | More about Semaglutide | ||||||||
| Ratings & Reviews | |||||||||
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Metformin has an average rating of 6.8 out of 10 from a total of 656 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 19% reported a negative effect. |
Semaglutide has an average rating of 6.9 out of 10 from a total of 2706 ratings on Drugs.com. 57% of reviewers reported a positive effect, while 20% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Metformin side effects |
View all Semaglutide side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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Lower cost generic |
N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||
View all Metformin prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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N/A |
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| Brand Names | |||||||||
| Glumetza | Ozempic, Rybelsus, Wegovy | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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4.5 hours |
168 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 378 drugs are known to interact with Metformin:
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A total of 274 drugs are known to interact with Semaglutide:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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March 03, 1995 |
December 05, 2017 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.