Comparing Femara vs Metformin
Femara Remove Femara from your drug comparison | Metformin Remove Metformin from your drug comparison |
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Femara letrozole Remove Femara from your drug comparison | Metformin Remove Metformin from your drug comparison | ||||||||||||||||
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Femara is a treatment that may be used to reduce the risk of breast cancer recurrence in postmenopausal women and also to increase the chance of ovulation in women with polycystic ovary syndrome.... View more |
Metformin improves how the body responds to insulin and it is effective for the treatment of type 2 diabetes. Taste disturbances, diarrhea, and other stomach-related side effects are common side... View more |
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Prescription only |
Prescription only |
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Ratings & ReviewsRecent helpful reviews |
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6.9
For Breast Cancer: I have been on Femara for almost a year. At first I had nearly constant hot flashes/night sweats. Was started on Effexor with nearly immediate relief. Have had increasingly painful joint and muscle pain, especially in my knees. Nothing seems to be helping much with that and it has been a major detriment to my quality of life. Have recently added Magnesium, Fish Oil and Glucosamine/Chrondroitin to the Calcium and D3 I had been taking. Hopefully this will ease the joint stiffness and pain. I am 52 and some days feel 92. Still I am cancer free so far, so I will continue to take Femara. |
7.0
For Polycystic Ovary Syndrome: I am 27 and I have PCOS and endometriosis.I was told to lose 20kg before I could be operated to remove the endo. My doctor prescribed me Metformin 500mg for the first week and thereafter increase it to 1000mg a day. It's my 9th day of being on Metformin and I have lost 2.25kg in this time. My goal is to get to 55kg and I'm currently 71kg. I haven't really experienced the awful diarrhoea however I have been getting crazy heart palpitations. Also,when I increased the dosage I found that within the day I would experience some bad stomach cramps but that's about it. Hoping to achieve my weight loss. For Polycystic Ovary Syndrome: I got my first period when I was 11 and was regular up until I was 14 and then they stopped. Fast forward to 2015 and I hadn't had a period at all for 5 years. I decided to finally do something about it, I was actually enjoying the lack of periods to be honest! I had some tests done and the diagnosis of PCOS was confirmed. My doctor put me on metformin 500mg twice a day and I hated it. I was so nauseous for the first two weeks, frequent diarrhea and lots of dizziness but it all passed. After that I began to have more energy aaaaand my period came back. It makes you feel really gross at first but if you can survive the first few weeks you'll be all good! |
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Drug Class |
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Side Effects |
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Common side effects include: bone fracture, arthralgia, edema, dizziness, fatigue, hypercholesterolemia, osteoporosis, and flushing. See the full Femara side effects document. |
Commonly reported side effects include: lactic acidosis, diarrhea, nausea, nausea and vomiting, vomiting, and flatulence. See the full metformin side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all Femara prices and generic prices |
View all metformin prices |
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Generic Availability |
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Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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N/A |
Glumetza, Riomet, Riomet ER | ||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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48 hours |
4.5 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
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FDA Alerts |
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N/A |
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Drug Interactions |
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A total of 86 drugs are known to interact with Femara:
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A total of 344 drugs are known to interact with metformin:
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Alcohol/Food/Lifestyle Interactions |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions |
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First Approval Date |
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July 25, 1997 |
March 03, 1995 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
For Breast Cancer: Caused me weight gain, serious hot flashes, did not have joint pain, headaches, or dizziness before starting this medication. I know these are listed possible side-effects, however, these do cause some functionality issues.