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Femara and Hot Flashes: What Users Say

Hot flashes: mentioned by 15 users (22.4%)

Based on user experiences from 67 Femara reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

joint pain 44.8%
hot flashes 22.4%
hair loss 19.4%
pain 19.4%
muscle pain 11.9%
brain fog 10.4%
weight gain 10.4%
bone pain 9.0%
fatigue 7.5%
night sweats 7.5%

Reviews for Femara

Commonly mentioned side effects
  • ros...
  • February 8, 2012

For Breast Cancer "I had many side effects, including hot flashes, confusion, stomach problems, vaginal dryness, tired easily, and bone weakening. On the bright side, I have had no recurrence, and it is now 12 years since my diagnosis with lymph node involvement."

7 / 10
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297 Report
  • Smi...
  • May 15, 2017

For Breast Cancer "I've been taking Femara for a little over 5 months and have yet to experience any side effects whatsoever. I'd been warned about hot flashes, night sweats, joint pain, muscle pain, and so far nothing. I have two smallish tumors in one breast that we caught very early on, and at my 4-month ultrasound they've decreased by about 50%. I'll have a nipple-sparing mastectomy in about 2 weeks with DIEP flap reconstruction... the grossest part of this whole episode, in my opinion... followed by radiation. No chemo here, just a very healthy mostly vegetarian diet and tons of walking. I'm 69, 5'6'', 135 pounds, and so far consider myself about the luckiest cancer patient anywhere. Maybe I'll start feeling sick at some point, but not yet. Hang in there, ladies!!"

10 / 10
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200 Report
  • Eri...
  • February 9, 2013

For Breast Cancer "I have been on Femara for almost a year. At first, I had nearly constant hot flashes and night sweats. I was started on Effexor with nearly immediate relief. I have had increasingly painful joint and muscle pain, especially in my knees. Nothing seems to be helping much with that, and it has been a major detriment to my quality of life. I have recently added Magnesium, Fish Oil, and Glucosamine/Chondroitin to the Calcium and D3 I had been taking. Hopefully, this will ease the joint stiffness and pain. I am 52, and some days I feel 92. Still, I am cancer-free so far, so I will continue to take Femara."

7 / 10
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219 Report

Frequently asked questions

  • tin...
  • Taken for 6 months to 1 year
  • April 29, 2023

For Breast Cancer "Awful! I've been on Femara for about 8 months. And since I started, I seem to have every single side effect. My joint and muscle pain is excruciating. In no particular order, I suffer with body pain (fingers, hands, shoulders, chest, back, sides, hips, legs, feet - basically everything head to toe). Plus, weight loss, hot flashes, headaches, dizziness, thinning of hair, dry mouth, high BP, night sweats. Even my scalp is tender. Chest pain that radiates to upper arms, shortness of breath, overall depression. Chills, insomnia, intestinal pain - sharp pains, plus dull aching. Constant feelings of nausea, diarrhea, constipation. I'm afraid to eat but also have little appetite. Brain fog, shortness of breath. Feeling that I am just going to die. Sitting up in pain all night. I hurt everywhere - too sick to move; too sick to cry. Feels like I am going to have a heart attack. Can’t lie down, can’t stand up. Full body chills, hands shaking. Haven't slept through the night in months."

1 / 10
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46 Report
  • Anonymous
  • July 14, 2009

For Breast Cancer, Metastatic "I have been using Femara for 8 months, and I have been having very few side effects. I get the hot flashes only once in a while now. I do have some joint pain, but that has been easy to tolerate. If that means I will have a longer life, only God knows that. There is always hope, just keep the faith and have no doubt in the medicine, doctors and mostly God."

9 / 10
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203 Report

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  • dog...
  • Taken for 2 to 5 years
  • July 19, 2014

For Breast Cancer, Adjuvant "I was diagnosed in 2009, had lumpectomy, chemo, radiation. Managed to continue working through it all. Then took tamoxifen for 2 1/2 years... had horrible muscle cramping and hot flashes, switched to letrozole after determining I was postmenopausal. The major muscle cramps lessened considerably, as did the hot flashes. I took this for 2 1/2 years, just stopping 3 weeks ago. I have muscle, joint, bone achiness 24/7, no energy, tired always, feel like I'm in a fog, tinnitus, heartburn, slow metabolism with weight gain. How long will it take to reverse all of these side effects now that I no longer take it? I even quit taking ibuprofen because it doesn't do anything for the pains. I am now 2 months from being 50 years old."

5 / 10
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141 Report
  • Sus...
  • September 7, 2010

For Breast Cancer "I'm 4 years status post breast CA and doing well... no recurrence for my Stage IIIA. I started taking tamoxifen, then my oncologist switched me to Femara. I do have frequent hot flashes (whew!) and joint and bone pain that worsens with being tired. Overall, I am able to tolerate the medication, and my oncologist believes it is the treatment of choice for me. The side effects of being without estrogen are worse than the Femara side effects. I know the drug is working as having no estrogen produced results in atrophic vaginitis, decreased sex drive, and other female issues that are bothersome. But, in the big picture of life, it's a small price to pay to be, and hopefully stay, cancer free. I will continue to use Femara!"

8 / 10
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174 Report

More FAQ

  • Mrs...
  • Taken for 1 to 6 months
  • September 21, 2013

For Breast Cancer "I was diagnosed with breast cancer (stage 2) - underwent 6 months of chemo and 6 weeks radiation. My hair regrowth was pretty quick but began thinning significantly after about a year of Tamoxifen usage (could see my scalp pretty clearly in the front and on top of my head). My doctor switched me to Femara about 2 months ago - side effects include lots of hot flashes (about 6-10 daily) and weight gain which I am combating by working out every day and cutting my calories. I am prayerful that I don't experience any more hair loss or the joint pain that I keep reading about. Everyone, hang in there!"

7 / 10
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148 Report
  • Jil...
  • November 30, 2015

For Breast Cancer "Stage 4 HER2-positive breast cancer was found in 2011. After a double mastectomy (additionally, 6 other surgeries due to Staph infection and failed reconstruction attempts), 6 months of 2 types of chemotherapy, including Neulasta booster shots after each infusion, a total of 1 year of Herceptin chemo infusions, 6 weeks of daily radiation, then 8 years of Femara. Been taking this medication daily since August 2012. Hot flashes and night sweats are awful. Anxiety occasionally. Easily out of breath after any activity. Difficulty maintaining focus and frequent forgetfulness. 3 years with this medication and chest, bone, and joint pain is intensifying. 5 more years to go. CANCER FREE STILL."

10 / 10
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116 Report
  • min...
  • September 12, 2015

For Breast Cancer "In 2011, I was diagnosed with stage 3A invasive ductal breast cancer. I went through chemo for 4 months and had a double mastectomy in March 2012, followed by 6 weeks of radiation. I was put on tamoxifen for a year and then Femara, which I currently take now. The biggest thing with Femara is feeling constantly tired and 'foggy'. I can handle the hot flashes (we live in Minnesota, where the winter lasts for 6 months) - I just walk around outside with a t-shirt on, and I'm good to go! Lately, I have been experiencing hair loss, and I don't know if it's due to the Femara. Anyone else have this problem? Please let me know. Hang in there, beautiful ladies (& men)."

7 / 10
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96 Report
  • Can...
  • Taken for 1 to 6 months
  • August 18, 2015

For Breast Cancer "Diagnosed May 2014 with Stage 3 Breast cancer after chemo, removal of the tumor & lymph nodes, radiation. I started Femara, been on it almost 6 months and I have daily joint & muscle pain, fatigue, hot flashes, and most of all weight gain. I'm really trying to eat healthy and exercise, but working a full-time job, it's a tough routine to keep up with every day (55 and post-menopausal). But hey, I'm still here and hopeful the medication does a good job of keeping the cancer at bay. Doing my best with the symptoms."

9 / 10
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90 Report
  • Gon...
  • Taken for 1 to 2 years
  • May 2, 2018

For Breast Cancer "1.7 years, loss of hair, hot flashes, shoulder, elbow, hip pain, dry mouth, high cholesterol, high glucose, high BP... But if it keeps cancer from returning, the side effects, hopefully temporary, will have been worth it."

8 / 10
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58 Report
  • Anonymous
  • March 31, 2018

For Breast Cancer "Daily hot flashes and night sweats seem to be my worst side effects, especially when I'm hit with intense anxiety every time. My scalp is tender, and I've had hair thinning. I also have pain in my joints. But I do not want the cancer to come back. Invasive lobular carcinoma. Bilateral mastectomy."

6 / 10
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52 Report
  • Jew...
  • Taken for 1 to 2 years
  • May 2, 2016

For Breast Cancer "Stage 2b or stage 3 according to the onc nurse. Invasive lobular cancer. One year on letrozole. Just had a bone cancer scare, but a negative bone scan. Hot flashes, sweats, bone fracture, not injury. Some bleeding from genital tissues. Also had a 10 lb weight loss. Anyone else with bleeding and weight loss? Lots of back pain, already had osteoarthritis."

8 / 10
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42 Report
  • Anonymous
  • September 20, 2011

For Breast Cancer "My main concern was the memory loss. I could tolerate the hot flashes. The 'morning sickness' was undesired and difficult, but the memory loss is something I can't deal with."

5 / 10
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127 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.