Comparing Femara vs Ibrance
| Femara | Ibrance |
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| Femara (letrozole) | Ibrance (palbociclib) |
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Prescription only
Femara is a treatment that may be used to reduce the risk of breast cancer recurrence in postmenopausal women and also to increase the chance of ovulation in women with polycystic ovary syndrome... View more |
Prescription only
Ibrance is a CDK4/6 inhibitor that may be used to treat advanced or metastatic hormone-receptor-positive (HR+), human epidermal growth factor receptor 2 negative (HER2-) breast cancer in combination... View more |
Related suggestions Breast Cancer
Breast Cancer, Metastatic
Popular comparisons
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| More about Femara (letrozole) | More about Ibrance (palbociclib) | ||||||||||||||||
| Generic Status | |||||||||||||||||
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No lower-cost generic available |
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| Ratings & Reviews | |||||||||||||||||
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Femara has an average rating of 6.9 out of 10 from a total of 62 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 16% reported a negative effect. |
Ibrance has an average rating of 6.6 out of 10 from a total of 69 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 33% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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Common side effects include:
See also: Femara side effects in more detail. |
Common side effects include:
See also: Ibrance side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Femara prices and generic prices |
View all Ibrance prices |
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| Dosage Form(s) Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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48 hours |
29 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 100 drugs are known to interact with Femara:
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A total of 416 drugs are known to interact with Ibrance:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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July 25, 1997 |
February 03, 2015 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
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N/A |
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| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.