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Medically reviewed by Last updated on May 6, 2024.

What is liposarcoma?

Liposarcoma is a type of cancer that most often develops from fat cells. It is most commonly found in your legs or thighs, but it can also be found in your abdomen, back, arms, chest, and neck. Liposarcomas most often occur in people between the ages of 50 to 70 years old.

What causes liposarcoma?

The exact cause of liposarcoma is not known, but it may be caused by damaged genes. Liposarcomas more commonly occur in an area of your body that has been injured. You may be at a higher risk if have received radiation treatment in the past.

What are the different types of liposarcoma?

Liposarcoma may be a low-grade or high-grade tumor. A low-grade tumor is usually slow growing and does not spread to other areas of your body. A high-grade tumor is usually larger and often spreads to other areas in your body. The type of liposarcoma that you have will depend on the kind of cells that make up your tumor. Your liposarcoma may be any of the following:

What are the signs and symptoms of liposarcoma?

Liposarcomas are usually painless and slow growing. You may be able to see or feel it under your skin. You may have pain if your tumor grows and presses on your nerves and blood vessels. Depending on where your tumor is, you may have any of the following:

How is liposarcoma diagnosed?

Your healthcare provider will examine you and ask about your symptoms and other medical conditions. Your provider may feel the tumor and area around it. You may also need any of the following tests:

How is liposarcoma treated?

Treatment options

The following list of medications are related to or used in the treatment of this condition.

What are the risks of liposarcoma?

With surgery, you may bleed more than expected or get an infection. If surgery was done on your arm or leg, you may have trouble doing your usual activities. Even with treatment, the liposarcoma may grow back, spread, or be life-threatening. You may need to have another surgery and other treatments to treat cancer that comes back. If your liposarcoma is not treated, your cancer may spread to other areas of your body. The cancer cells may damage your organs and your symptoms may worsen. This can be life-threatening.

How can I manage my symptoms?

When should I contact my healthcare provider?

When should I seek immediate care or call 911?

Care Agreement

You have the right to help plan your care. Learn about your health condition and how it may be treated. Discuss treatment options with your healthcare providers to decide what care you want to receive. You always have the right to refuse treatment. The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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