Comparing Lyrica vs Topamax
| Lyrica (pregabalin) | Topamax (topiramate) |
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| Lyrica (pregabalin) | Topamax (topiramate) |
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Prescription only
Lyrica can help relieve nerve pain and control seizures but it is likely to cause drowsiness. Prescribed for Neuropathic Pain, Neuralgia, Fibromyalgia, Diabetic Peripheral Neuropathy, Postherpetic... View more |
Prescription only
Topamax may be prescribed either alone or in combination with other medications for the treatment of certain types of epilepsy, or it may be given for the prevention of migraine. Drowsiness is a... View more |
Related suggestions Popular comparisons
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| More about Lyrica (pregabalin) | More about Topamax (topiramate) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Lyrica has an average rating of 6.4 out of 10 from a total of 931 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 26% reported a negative effect. |
Topamax has an average rating of 6.2 out of 10 from a total of 645 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 29% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Lyrica side effects |
View all Topamax side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Lyrica prices |
View all Topamax prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other pregabalin brands include: Lyrica CR | Other topiramate brands include: Eprontia, Qudexy XR, Trokendi XR | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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6.3 hours |
56 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 287 drugs are known to interact with Lyrica:
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A total of 291 drugs are known to interact with Topamax:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 30, 2004 |
December 24, 1996 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.