Topamax and Weight Loss: What Users Say

• Anonymous
• February 24, 2012

For Weight Loss (Obesity/Overweight) "Topamax is amazing. I originally took it 6 years ago to prevent migraines and lost 80 lbs as a bonus. At that time, my doctor and I speculated that it would someday be approved for weight loss because I was not his only patient to report changes in the taste of carbonated beverages and chocolate while taking the medication. I also noticed that I did not dream about food while taking the medication, but within 3 months of changing medications, food re-entered my dream content. I am now back on the medication to address chronic pain issues and have already found the same results in weight loss, taste changes, and dream content."

• Par...
• January 16, 2020

For Migraine Prevention "On Topamax, and 6 years ago I had what I thought was a seizure and spots in my right eye. The spots NEVER went away. Other symptoms of this horrible drug - ITCHING, SEIZURES, HAIR LOSS, EXTREME HOT FLASHES, EXTREME WEIGHT LOSS. My doctor never, ever cared about any of it. I quit this awful drug in October 2016. Had a minor stroke shortly after. Do not take this drug if you want to stay healthy and keep your eyesight. I filed a complaint with the FDA, and of course, they didn’t care either. This drug is a result of greedy drug companies and the FDA being lobbied to allow such a destructive drug. Doctors don’t care either. They all just keep making their money while patients end up with permanent damage that CANNOT be fixed."

• Boj...
• March 16, 2014

For Migraine Prevention "I'm 50 years old and have suffered from migraines since I was about 12 years old. Too long! I've taken every medicine possible for prevention or cure with little or no relief. Too many trips to the ER for shots...the only real fix; then back home in a dark room for much-needed sleep. When my internist suggested Topamax, I jumped at the opportunity. Boy, I'm happy that I did. Yes, I had the initial side effects, lost 35 lbs originally (gained 10 back), have tingling in my fingers & toes but only in the winter when I'm cold. Very manageable. I don't drink pop, but tried one. Wow...it was flat. I do struggle with words at times, but still manageable. My 3/week migraines now down to 1/month are generally managed with Excedrin Migraine. A"

• Anonymous
• July 8, 2010

For Weight Loss (Obesity/Overweight) "I was on Topamax for almost 3 years, was prescribed it for severe migraines. The weight loss was a side effect, a nice one though! I didn't need to lose much to begin with, maybe 20 lbs or so, and I started to notice that I went from the 140s to the 120s. I am now off this medicine as I have been migraine-free for almost two years and the only bad thing I can say is that the weight comes right back on if you're not watching very carefully. Also, HUGE side effect was the medicine caused my body to not sweat, which caused severe overheating. It's a less common side effect, but a very super important one to be aware of."

• ado...
• March 27, 2013

For Bipolar Disorder "I have had a good experience after trying to find the right cocktail for several years. I have a very high-stress job and my anxiety is put to the test daily. It is not clinically significant at this point, and I can only attribute that to finally having my medicines right. I am taking Wellbutrin, Lamictal, Topamax, and Zoloft at pretty low dosages for each. I did lose about 70 pounds. After over a year on the Topamax, my normal appetite has started to return and I have gained back about 10 pounds, but I still have self-control that I lacked when I was fighting depression, which is now at bay."

• Nom...
• November 10, 2014

For Migraine Prevention "I started taking Topamax about 3 years ago. Began at 25mg a day for a week. The second week I was supposed to move up to 50, the third week to 75mg, and then finally to 100mg on the fourth week. I never really had to move past 25mg. My migraines all but stopped after a month of being on the medication and at the lowest dose. I had all the side effects - tingling, weight loss (very happy about it too), forgetting certain words, and the nasty taste of soda. That was okay because I only drink it very rarely anyway. I was getting 1-2 migraines a week and now, I may have 1-2 a year. Most of the side effects seemed to have faded with time as well. Very, very pleased with this medication."

• Anonymous
• January 14, 2012

For Bipolar Disorder "I started this medication for weight loss, bipolar, migraines. Seems like it may just be perfect...hopefully. I just finished my first week and lost 3 pounds! I workout 5-6 days a week, but due to antidepressants making me gain so much weight, regardless of my diet and exercise, I am fat. So today stepping on that scale and seeing 3 POUNDS LIGHTER! I am a very moody person, but the medicine seems to be making it right, moods seem to be very level. And haven't had one migraine! No side effects other than weight loss and loss of appetite... can't complain about that!"

• rog...
• Taken for 5 to 10 years
• July 21, 2013

For Seizure Prevention "This is for the Newbies out there. I started this medication when I was 15. Had my first seizure a few days before my 15th birthday. The first side effect you will experience is sleepiness, don't fight it. Let your body get a nap between 1-3, which I found to be the best time. I sleep for 1 hour and still can fall asleep at night. I am 21 now. Some advice to you: whenever you don't feel like eating, I found that sweet tea gets me hungry, find that X factor in you. The weight loss is insane. I lost 40 pounds in 6 months just by breathing. Now, sleep patterns are important. If the average person needs 8 hours, you and I need 9-10 MINIMUM. Also, try to take the dose at the same time every day, you will fall asleep faster. Hang out to see sunrise."

• Cas...
• June 10, 2016

For Weight Loss (Obesity/Overweight) "Ok, so I am going on my third week of Topamax. I have seizures, uncontrollable migraines, and obesity, so let me begin with saying this. I have noticed a significant change in my body as far as the weight loss goes - 6 pounds since I have been on it and still losing. However, I have lost my appetite, I have no desire to eat. I may eat only once a day, that's the only downside I have noticed. I have noticed a change in carbonated drinks, they don't taste the same anymore. I am currently coming off Tegretol, which was only treating my seizures, and I was gaining so much weight. So, I'm thankful that Topamax is working for me, and I only have to take one pill a day to treat all my ailments."

• Anonymous
• August 1, 2009

For Diabetic Peripheral Neuropathy "After having developed neuropathy post surgery, I was suffering daily. I had tried Neurontin with little relief and was prescribed Topamax initially at 25mg. Over the last 6 years, I've been titrated up to 300 mg and can tell you that this drug has helped tremendously. Initially, I had common side effects: difficulty finding words, I lost weight about 20 pounds, and found that I had some tingling in my hands and feet. These issues generally resolved in time, or I have just grown accustomed to them. For anyone who initially has issues with the side effects, try and stick with the medicine for a little bit unless totally intolerable, it gets better."

• Lin...
• Taken for 1 to 2 years
• April 29, 2015

For Weight Loss (Obesity/Overweight) "I started taking 50 mg of Topamax for the first month and went up to 100mg for the next three months. Lost 40 pounds. For the next year and a half I have kept off the weight but have not lost any more. I still need to lose 30 more pounds, but have seemed to plateaued. And I am at 200 mg now. Don't know what to do."

• sur...
• July 7, 2010

For Bipolar Disorder "I have taken Topamax for the last 8 months as a mood stabilizer. It has worked great. Not only has it helped with my moods, but it also helped me lose more than 30 lbs without struggling to lose it. It was easy and great. I am happy again, and I don't feel like I want to chew off everyone's head when I start to get irritable or around 'that time of month'. It's been a lifesaver."

• Jen...
• May 30, 2015

For Weight Loss (Obesity/Overweight) "I was on 25 mg to start and ended up taking 100. I lost weight. But the price I paid in side effects was not worth it. I lost so much hair that when I try to braid it, it's like braiding tiny strands of dental floss. It looks so ridiculous, long I had to chop it all off just to conceal how grossly thin it is. People call it Dopamax for a reason. It made my memory Swiss cheese, and when I had to process information, it felt like fighting through seaweed. The worst side effect was the depression. This stuff makes me downright suicidal. It helped me lose about 80 pounds by starvation. I never wanted to eat. I became anemic. If you've never had that before, you'll find simple physical tasks to feel like they're inciting heart attacks."

• 4gr...
• July 14, 2008

For Bipolar Disorder "Have used Topamax for over 2 years, in conjunction with Wellbutrin. Never knew that life was quite like this. I am now almost 53 years old. To think that I lived so many years never being diagnosed with Bipolar Disorder. I am so happy that life is so wonderful because of Topamax. Only side effect has been weight loss but, that really is a good thing. It is wonderful to be back at my true weight because the bipolar disorder is now managed."

• Anonymous
• July 16, 2014

For Migraine Prevention "By the time I started Topamax, I was getting migraines 2-4 days a week. Topamax seemed like the best fix. And for a while, it was. My migraines significantly reduced, though I did get most of the common side effects: slight tingling in my fingers, carbonated beverages tasted gross, and weight loss. My main warning about this medicine is weight loss. It seems to be paraded as a benefit, and to some it may be, but if you are already naturally slim, pay very close attention. I wound up dropping to an unhealthy weight despite all attempts to counter it, and it's ultimately why I had to stop Topamax. I was unwillingly wasting away. When I stopped, my migraines returned in short order, and I'm still looking for an alternative that works."

• Ood...
• Taken for 1 to 2 years
• November 28, 2015

For Migraine Prevention "Topamax is by far the best migraine preventative I have ever tried. I take 100mg at night and have even been on 200mg - 1 100mg in the AM and 1 100mg in the PM. My neurologist and I discussed Topamax and figured it was worth a shot since my chronic, daily migraines were uncontrollable and I was getting Imitrex injections almost every week and could no longer take Toradol. Unlike other people, I have very few side effects. I weaned off Topamax once to try Gabapentin but it by itself wasn't enough and my migraines returned full force. Very few side effects: trouble finding words, thirst, and weight loss (not that I mind). Topamax is a wonderful drug and a LIFESAVER. It and my Gabapentin together is my divine combo!"

• Hal...
• Taken for 1 to 6 months
• November 19, 2019

For Migraine Prevention "On this medication to prevent migraines. It works like a charm. I had migraines almost daily, and now I only have them the day before my period starts. I have not had the weight loss side effect people talk about, though."

• Jen...
• November 15, 2016

For Migraine Prevention "I have been taking 75 mg Topamax once a day for about 10 years now. I have gone as far as taking 100 mg until I started not being able to get the words out that I was thinking of. That side effect has not completely gone away but is better. When I first started, I did have the tingling in my hands and feet, but it was no more than like having carpal tunnel. I also have the weird taste where soda tasted flat and tomatoes taste weird. I did lose a little weight. The tingling went away, I adjusted to just not drinking soda. And tomatoes started to taste fine. I also take Sumatriptan for when I still do get a headache. However, the headaches are much fewer and further between. I will get a cluster of them about every six months, but still better."

• fgh...
• July 2, 2008

For Bipolar Disorder "I have been off and on Topamax for about 5 years now, and I must say that it works better for bipolar mood stabilization than any other one out there. The one thing I love the most about this medicine is that it is helping me lose weight. They need to put in the time to verify that this drug is, in fact, a mood stabilizer because it certainly does help with bipolar disorder."

• Mar...
• Taken for 1 to 2 years
• October 31, 2015

For Migraine Prevention "I felt compelled to write a review, as I was on Topamax (or should I say Dopamax?!) for about 2 years. I started this medication when I was 21 and was so desperate to find something that would actually help my ongoing migraines. Personally, the side effect symptoms FAR outweighed the benefits. I started out on 25 mg a day and gradually increased to 100 mg. As soon as I got on this, the side effects came rolling in. Before I knew it, my memory was completely gone. In daily conversation, I couldn't think of simple words, names, or phrases. I knew what I wanted to say but couldn't form the words to do so. The worst of all, it really affected my grades in college. I used to have awesome memorization skills. Unfortunately, I would study for hours upon hours and still wouldn't do well as I would have 'brain fog' during tests, etc. Another side effect I experienced was weight loss. I lost around 25 lbs., HOWEVER, I don't believe all of this was ultimately from Topamax. I'd definitely say it suppressed my appetite, but I really changed my eating habits and worked out daily. It helped with my first few pounds and got me motivated to do the rest. On the plus side, I saw a significant difference in the amount of migraines I received. It was a night and day difference in that aspect. However, approaching a year and a half on this medication, I couldn't take it anymore and had to get off. It wasn't worth it anymore. I don't think tapering off or stopping cold turkey on this really makes a difference. My mom stopped cold turkey, and I tapered off, as my doctor instructed me. I rebounded off this HORRIBLY, as did my mom. I was STARVING constantly after no longer taking it. This didn't just go away either. My body didn't feel leveled out and 'detoxed' from this for honestly about a year after. I not only gained back all my weight I lost, but plus some. Although everyone's body reacts differently, I highly do NOT recommend taking this. Not even for those desperate for weight loss. Losing weight from a medication like this is not sustainable long-term. I'm 24 now and am still affected by my choice of taking this. Topamax has ultimately ruined my memory to this day. I still cannot remember words or things. It changed me. Do not take this! There are other answers out there."

• Anonymous
• Taken for 6 months to 1 year
• November 28, 2012

For Migraine Prevention "I started taking Topamax in January of 2012 for migraines. I was getting one a day. I did experience brain fog at first, but I found that after about a month or two, I was mostly back to normal. I have experienced weight loss and loss of appetite, and I'm also lactose intolerant, so I'm trying to work on eating a healthy amount. I have found that drinking a lot of water really helps with the tingly feeling in my feet and hands!"

• ben...
• June 25, 2011

For Bipolar Disorder "Topamax helps tremendously with mixed bipolar and rapid cycling. However, I was an athlete at the time, rode cycling, and was a psychiatric nurse. I went from 120 to 105. This was not a bad experience for me. My manager illegally pulled me into her office and told me, granted she is not even an RN, that I had anorexia and an eating disorder, and illegally discriminated against me to stop me from working with eating-disordered patients. My doctor even told her I was normal and healthy, just solid muscle. P.S. Have you ever seen a serious road cyclist have an ounce of fat on them?"

• cad...
• Taken for 1 to 6 months
• November 27, 2013

For Seizure Prevention "This medicine was great in taking care of seizures, but I honestly felt like I was crazy most of the time. I lost weight, which I was happy with, but when it comes to the final review, I was a crazy, small person. I couldn't even call an order in on the phone because I couldn't think fast enough. I went back to my doctor and asked him to take me off this."

• mel...
• Taken for 5 to 10 years
• April 6, 2013

For Migraine Prevention "Began taking Topamax in 2006. Before starting on Topamax, migraines were lasting 4-5 days after onset, and frequency of approximately 3 times per month. I experienced some diarrhea, which subsided after breaking the dosage up throughout the day (200 mg daily). Additionally, I have experienced weight loss (a significant amount of 50 lbs) I could not afford to lose. However, the weight loss has subsided as well. Upon beginning the medication, I had trouble recalling words and memory loss. At this juncture, the side effects have since passed and so have the migraines. I experience 1-2 migraines quarterly. Topamax has been a lifesaver for me. I had tried many other migraine preventatives to no avail."

• mnp...
• November 12, 2019

For Migraine Prevention "I took 50 mg Topamax daily for migraines. Six months into it, I started noticing increasing hair loss and looked for answers, including having both hormones and thyroid checked. I reread the included drug information several times and found nothing about hair loss. At the point I had lost half my hair, I finally Googled Topamax hair loss and found it is a side effect of Topamax. Also during this time, I had extensive testing trying to find out why I was having increased period pain, and both my doctor and I missed that this is listed as a side effect. I stopped the medication six weeks ago because of the hair loss, but also putting on hold additional procedures considered for dealing with the menstrual pain as there is a good probability this was also caused by the Topamax. Two stars that I give the drug are only because of the 'bonus' side effect of the weight loss, which was the only hesitation that I had about stopping taking it, and the nominal reduction in the number of migraines I was experiencing."