Comparing Cymbalta vs Lyrica
| Cymbalta Remove Cymbalta from your drug comparison | Lyrica Remove Lyrica from your drug comparison |
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| Cymbalta duloxetine Remove Cymbalta from your drug comparison | Lyrica pregabalin Remove Lyrica from your drug comparison | ||||||||||||||||
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Cymbalta has antidepressant, anti-anxiety, and pain-relieving properties; however, it has been associated with a discontinuation syndrome on withdrawal even when tapered. Prescribed for Back Pain... View more |
Lyrica can help relieve nerve pain and control seizures but it is likely to cause drowsiness. Prescribed for Neuropathic Pain, Fibromyalgia, Diabetic Peripheral Neuropathy, Neuralgia, Postherpetic... View more |
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Prescription only |
Prescription only |
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Ratings & Reviews |
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Drug Class |
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Side Effects |
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Common side effects include: asthenia, constipation, diarrhea, dizziness, drowsiness, fatigue, hypersomnia, insomnia, nausea, sedated state, headache, and xerostomia. See the full Cymbalta side effects document. |
Common side effects include: infection, ataxia, blurred vision, constipation, diplopia, dizziness, drowsiness, fatigue, headache, peripheral edema, tremor, weight gain, visual field loss, accidental injury, and xerostomia. See the full Lyrica side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all Cymbalta prices and generic prices |
View all Lyrica prices and generic prices |
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Generic Availability |
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Dosage Form(s) Available |
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Brand Names |
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| Other duloxetine brands include: Drizalma Sprinkle, Irenka | Other pregabalin brands include: Lyrica CR | ||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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17 hours |
6.3 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4. |
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Pregnancy Category |
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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Drug Interactions |
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A total of 565 drugs are known to interact with Cymbalta:
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A total of 268 drugs are known to interact with Lyrica:
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Alcohol/Food/Lifestyle Interactions |
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Disease Interactions |
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First Approval Date |
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N/A |
December 30, 2004 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.