Comparing Lupron Depot vs Zytiga

For Endometriosis: I've finished my third cycle of lupron for endometriosis and it kicked my butt ! Each cycle includes an injection each month, for 6 months. Once I finish Lupron, I slowly have periods and each month the pain gets stronger. Last time was bad, but nothing like this. There's no way of describing it other then "Roid rage", I couldn't control my emotions. 2 1/2 months I was manic, I'm talking fighting fits of rage and sobbing on the floor. which is nothing like myself, I'm almost emotionless. Hot flashes, hair thinning, loss of sex drive. That last one which I hope doesn't affect you, surprisingly is one of the worst. Gained 30 lbs over 6 mths while dieting, Even with an extremely strict diet I have only managed to loose 2 pounds and it's been 2 and a half months since my last injection. All in all I'm not sure if I will go through another treatment of Lupron as all the side effects that affected me seem to get more intense each time.

For Endometriosis: I had a very similar experience to Lora C. I was a mess on Lupron and very much not myself. I couldn't control my emotions, I was either dead inside or crying, there was no in between. My night sweats were awful and I was mean all the time. The worst part was probably my memory. I had no recollection of anyone's name, I could recognize their face and the fact that I definitely know them, but never their names if I had met them after I was on Lupron. The shot also hurts like anything and hot flashes are real. I was consistently warm all of the time. Summer was unbearable. Also, the first few months were the worst endo pain I had ever felt. It was terrible. It finally went away after about month 4 or 5 and I was in a normal range of just feeling pressure down there. It wasn't nearly as painful, but always present.

For Prostate Cancer: I am 69. Was diagnosed with prostate cancer 10 months ago with PSA of 68%. I had the MRI which showed that the cancer had metastasised. Oncologist recommended Zytiga but, where I live (Hong Kong) it costs about HK$30,000 per month. Can't afford that. A medical friend suggested I try India. I did a lot of research and asked friends in India for recommendations and found a supplier at a good price for the generic. I have been taking the generic (Arbiterone - 4x250 micrograms +2 tabs of Predisnone per day) for the last six months. Within two months my PSA was down to 9% and was still at that level three months ago. Side effects – hot flashes, night sweating, and weight-gain. Urologist suggested Clonidine for the hot flashes – worked really well. I see my doctor again in three weeks' time. He is looking into Olaparib (also called Lynparza) and Ivermectin for me.

For Prostate Cancer: PSA 28 to 4 in one week. Fatigue only side effect. Prednisone effect- no pain in bad knee(which has nothing to do with prostate cancer).