Comparing Lupron Depot vs Zytiga

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
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Lupron Depot leuprolide

Zytiga abiraterone

Lupron Depot is a hormone deprivation treatment that may be used for the palliative care of advanced prostate cancer. The main side effects are hot flushes and general pain and it may cause... View more

Prescribed for Prostate Cancer. Zytiga may also be used for purposes not listed in this medication guide.

Prescription only

Common side effects include: decreased serum potassium, increased serum aspartate aminotransferase, increased serum triglycerides, fluid retention, and hypokalemia.

See the full Zytiga side effects document.

Pricing and Coupons

* Prices are without insurance

Quantity	1 kit
Dosage	7.5 mg/month
Per Unit^*	$1,854.72
Cost^*	$1,854.72

View all Lupron Depot prices and generic prices

Quantity	120 tablet
Dosage	250 mg
Per Unit^*	$94.80
Cost^*	$11,375.55

View all Zytiga prices and generic prices

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Generic Availability

Yes

Dosage Form(s) Available

Intramuscular kit
Intramuscular powder for injection, extended release

Oral tablet

Brand Names

Other leuprolide brands include: Camcevi, Eligard, Fensolvi, Lupron Depot-PED Other abiraterone brands include: Yonsa

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

4.25 hours

19 hours

CSA Schedule**

View glossary of terms.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category X Not for use in pregnancy

See the full Pregnancy Warnings document.

Category X Not for use in pregnancy

See the full Pregnancy Warnings document.

Drug Interactions

A total of 264 drugs are known to interact with Lupron Depot:

56 major drug interactions (151 brand and generic names)
207 moderate drug interactions (806 brand and generic names)
1 minor drug interactions (2 brand and generic names)

A total of 389 drugs are known to interact with Zytiga:

88 major drug interactions (294 brand and generic names)
279 moderate drug interactions (1141 brand and generic names)
22 minor drug interactions (49 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Taking abiraterone with food increases the amount of medicine that gets absorbed by the body. This... View more

Disease Interactions

First Approval Date

January 26, 1989

April 28, 2011

WADA Class

View World Anti-Doping Agency classifications.

N/A

More Information

Patient resources

Advanced Reading

Advanced Reading

Professional Resources

Prescribing Information

Prescribing Information

Related Treatment Guide

Prostate Cancer

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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