Comparing Loperamide vs Metoclopramide
| Loperamide | Metoclopramide |
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| Loperamide | Metoclopramide |
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Prescription and OTC
Loperamide effectively treats diarrhea in adults and children over the age of 2 years by slowing down the movement of the bowel. Children are especially sensitive to its effects, especially if they... View more |
Prescription only
Metoclopramide may be used short-term for the treatment of gastrointestinal reflux disease that is unresponsive to other medications or to treat diabetic stasis. Side effects may include sedation... View more |
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| More about Loperamide | More about Metoclopramide | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Loperamide has an average rating of 8.4 out of 10 from a total of 93 ratings on Drugs.com. 76% of reviewers reported a positive effect, while 10% reported a negative effect. |
Metoclopramide has an average rating of 3.9 out of 10 from a total of 521 ratings on Drugs.com. 28% of reviewers reported a positive effect, while 64% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Loperamide side effects |
View all Metoclopramide side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Loperamide prices |
View all Metoclopramide prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| A-D Anti-Diarrheal, Anti-Diarrheal, Diamode, Diar-Aid, Imodium, Imodium A-D, Kaopectate II, Neo-Diaral, Up and Up Anti-Diarrheal Solution View more | Gimoti, Maxolon, Reglan | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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10.8 hours |
8 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 353 drugs are known to interact with Loperamide:
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A total of 364 drugs are known to interact with Metoclopramide:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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N/A |
December 30, 1980 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.