Comparing Levothyroxine vs Metformin
| Levothyroxine | Metformin |
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| Levothyroxine | Metformin |
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Prescription only
Levothyroxine replaces missing thyroxine and is the preferred medicine to treat hypothyroidism. The dosage of levothyroxine needs to be tailored for each individual and there is a fine line between... View more |
Prescription only
Metformin improves how the body responds to insulin and it is used to treat type 2 diabetes. Taste disturbances, diarrhea, and other stomach-related side effects are common side effects. Metformin is... View more |
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| More about Levothyroxine | More about Metformin | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Levothyroxine has an average rating of 5.2 out of 10 from a total of 877 ratings on Drugs.com. 41% of reviewers reported a positive effect, while 45% reported a negative effect. |
Metformin has an average rating of 6.8 out of 10 from a total of 660 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 19% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Levothyroxine side effects |
View all Metformin side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Levothyroxine prices |
View all Metformin prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Eltroxin, Ermeza, Euthyrox, Eutroxsig, Evotrox, Levo-T, Levolet, Levoxyl, Novothyrox, Synthroid, Thyquidity, Tirosint, Tirosint-Sol, Unithroid View more | Glumetza | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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240 hours |
4.5 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category A
Studies show no risk
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 239 drugs are known to interact with Levothyroxine:
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A total of 380 drugs are known to interact with Metformin:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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August 21, 2000 |
March 03, 1995 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.