Comparing Jardiance vs Xigduo XR

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Jardiance (empagliflozin)	Xigduo XR (dapagliflozin / metformin)	Enter another drug to compare

Jardiance (empagliflozin)

Xigduo XR (dapagliflozin / metformin)

Prescription only

Jardiance is an oral medication that may be used to treat type 2 diabetes, improve outcomes in people with chronic kidney disease, or reduce the risk of cardiovascular death in some populations... View more

Prescription only

Prescribed for Heart Failure, Type 2 Diabetes. Xigduo XR may also be used for purposes not listed in this medication guide.

More about Jardiance (empagliflozin)

More about Xigduo XR (dapagliflozin / metformin)

Ratings & Reviews

Jardiance has an average rating of 5.3 out of 10 from a total of 329 ratings on Drugs.com. 40% of reviewers reported a positive effect, while 42% reported a negative effect.

Xigduo XR has an average rating of 7.3 out of 10 from a total of 17 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 24% reported a negative effect.

View all 329 reviews

View all 17 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Yeast infection (20.7%)
Thirst (10.6%)
Frequent urination (10.3%)
Urinary tract infection (10.0%)
Dizziness (6.1%)
Tiredness (6.1%)
Lightheadedness (5.8%)

View all Jardiance side effects

View all Xigduo XR side effects

Drug Class

SGLT-2 inhibitors

Antidiabetic combinations

Generic Availability

No lower cost generic approved

Pricing and Coupons * Prices are without insurance

Quantity	30 each
Strength	25 mg
Per unit^*	$22.73
Cost^*	$681.93

View all Jardiance prices

Quantity	60 tablet, extended release
Strength	5 mg-1000 mg
Per unit^*	$10.84
Cost^*	$650.21

View all Xigduo XR prices

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Dosage Forms

Oral tablet

Oral tablet, extended release

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

12.4 hours

12.9 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 432 drugs are known to interact with Jardiance:

2 major drug interactions (10 brand and generic names)
428 moderate drug interactions (1940 brand and generic names)
2 minor drug interactions (12 brand and generic names)

A total of 480 drugs are known to interact with Xigduo XR:

25 major drug interactions (136 brand and generic names)
443 moderate drug interactions (2113 brand and generic names)
12 minor drug interactions (42 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood... View more

MetFORMIN should be taken with meals, and excessive alcohol intake (either short-term binge... View more

Disease Interactions

First Approval Date

August 01, 2014

October 29, 2014

WADA Class View classifications

N/A

More Information

Patient Resources

Jardiance uses

Xigduo XR uses

Professional Resources

Prescribing information

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Jardiance vs Xigduo XR

See also:

Ozempic

Rybelsus

Wegovy

Farxiga

Lasix

Kerendia

Furoscix

Finerenone

Dapagliflozin

Semaglutide

Further information

Comparing Jardiance vs Xigduo XR

See also:

Further information

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