Comparing Janumet vs Rybelsus
| Janumet (metformin / sitagliptin) | Rybelsus (semaglutide) |
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| Janumet (metformin / sitagliptin) | Rybelsus (semaglutide) |
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Prescription only
Prescribed for Type 2 Diabetes. Janumet may also be used for purposes not listed in this medication guide. |
Prescription only
Rybelsus (semaglutide) is an oral medicine that can be used as a first-line medication to improve blood sugar control in adults over the age of 18 with type 2 diabetes. It works by mimicking the... View more |
Related suggestions Type 2 Diabetes
Popular comparisons
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| More about Janumet (metformin / sitagliptin) | More about Rybelsus (semaglutide) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Janumet has an average rating of 6.3 out of 10 from a total of 66 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 29% reported a negative effect. |
Rybelsus has an average rating of 6.5 out of 10 from a total of 303 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 22% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Janumet side effects |
View all Rybelsus side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Janumet prices |
View all Rybelsus prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other metformin / sitagliptin brands include: Janumet XR, Zituvimet, Zituvimet XR | Other semaglutide brands include: Ozempic, Wegovy | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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17.6 hours |
168 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 405 drugs are known to interact with Janumet:
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A total of 274 drugs are known to interact with Rybelsus:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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March 30, 2007 |
September 20, 2019 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
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Basaglar
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Soliqua
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Toujeo SoloStar
Toujeo (insulin glargine) is an injection used to treat type 1 or type 2 diabetes. Includes Toujeo ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.